Publications by authors named "Ariana Alavi"
Iran J Microbiol
June 2024
Article Synopsis
- Lipoarabinomannan, a component of mycobacterial cell surfaces, acts as an immunostimulant, triggering anti-bacterial cytokines like TNF-α and IL-12 during infections.
- In this study, female Bulb/c mice were divided into three groups: one received just the BCG vaccine, another received BCG with mannan adjuvant, and the last was a control group, with serum levels of various inflammatory factors measured.
- Results showed that the group with BCG and mannan adjuvant had significantly higher levels of IL-12, TNF-α, and IgG compared to those receiving only BCG or the control, while IgM levels were higher in the
Iran Biomed J
September 2023
Article Synopsis
- Mannoproteins, which are glycosylated proteins, have significant biological roles and industrial applications; this study focuses on extracting mannan oligosaccharide from the yeast Kluyveromyces marxianus.
- Various methods, including Sevage, trichloroacetic acid, and hydrochloric acid (HCl), were tested for deproteinization, and the resulting products were analyzed for their chemical composition and extraction efficiency.
- The study found that the HCl method yielded the highest purity (95.4%) and most effective deproteinization (97.33%), suggesting it is the best method to remove impurities in mannan oligosaccharide extraction for future scaling efforts.
