Methylphenidate intoxications in children and adults: exposure circumstances and evidence-based dose threshold for pre-hospital triage.

Context: Methylphenidate intoxications mostly have a relatively mild course, although serious complications can occur.

Objective: We aimed to characterize methylphenidate exposures and reassess our current dose threshold for hospital referral (2 mg/kg).

Methods: In a prospective follow-up study, we analysed 364 consecutive methylphenidate exposures that were reported to the Dutch Poisons Information Center.