Automated detection of dental artifacts for large-scale radiomic analysis in radiation oncology.

Background And Purpose: Computed tomography (CT) is one of the most common medical imaging modalities in radiation oncology and radiomics research, the computational voxel-level analysis of medical images. Radiomics is vulnerable to the effects of dental artifacts (DA) caused by metal implants or fillings and can hamper future reproducibility on new datasets. In this study we seek to better understand the robustness of quantitative radiomic features to DAs.

The impact of the variation of imaging parameters on the robustness of Computed Tomography radiomic features: A review.

The field of radiomics is at the forefront of personalized medicine. However, there is concern that high variation in imaging parameters will impact robustness of radiomic features and subsequently the performance of the predictive models built upon them. Therefore, our review aims to evaluate the impact of imaging parameters on the robustness of radiomic features.

SYNERGxDB: an integrative pharmacogenomic portal to identify synergistic drug combinations for precision oncology.

Drug-combination data portals have recently been introduced to mine huge amounts of pharmacological data with the aim of improving current chemotherapy strategies. However, these portals have only been investigated for isolated datasets, and molecular profiles of cancer cell lines are lacking. Here we developed a cloud-based pharmacogenomics portal called SYNERGxDB (http://SYNERGxDB.

Qualitative Posttreatment Diffusion-Weighted Imaging as a Predictor of 90-day Outcome in Stroke Intervention.

Purpose: The aim was to assess the ability of post-treatment diffusion-weighted imaging (DWI) to predict 90-day functional outcome in patients with endovascular therapy (EVT) for large vessel occlusion in acute ischemic stroke (AIS).

Methods: We examined a retrospective cohort from March 2016 to January 2018, of consecutive patients with AIS who received EVT. Planimetric DWI was obtained and infarct volume calculated.