Gold removal from e-waste using high-intensity focused ultrasound.

The demand for rare and precious metals (RPMs), e.g. gold, is increasing, as these are used in the ever-increasing amount of electronics needed for technological development and digitalization.

Wireless and battery-operatable IoT platform for cost-effective detection of fouling in industrial equipment.

We present a novel internet of things (IoT) sensing platform that uses helical propagation paths of ultrasonic guided waves (UGWs) for structural health monitoring. This wireless sensor network comprises multiple identical sensor units that communicate with a host PC. The units have dedicated hardware to both generate and receive ultrasonic signals, as well as RF signals for use in triggering the sensors.

Evaluation of bone growth around bioactive glass S53P4 by scanning acoustic microscopy co-registered with optical interferometry and elemental analysis.

Bioactive glass (BAG) is a bone substitute that can be used in orthopaedic surgery. Following implantation, the BAG is expected to be replaced by bone via bone growth and gradual degradation of the BAG. However, the hydroxyapatite mineral forming on BAG resembles bone mineral, not providing sufficient contrast to distinguish the two in X-ray images.

Practical scale modification of oleogels by ultrasonic standing waves.

Lipid-based materials, such as substitutes for saturated fats (oleogels) structurally modified with ultrasonic standing waves (USW), have been developed by our group. To enable their potential application in food products, pharmaceuticals, and cosmetics, practical and economical production methods are needed. Here, we report scale-up of our procedure of structurally modifying oleogels via the use of USW by a factor of 200 compared to our previous microfluidic chamber.

FEM-based time-reversal enhanced ultrasonic cleaning.

Pipe fouling is a challenging problem in many industrial applications. Current cleaning techniques require halting the production during the cleaning phase and the existing methods are unable to do targeted cleaning, even though fouling is often localized to certain areas inside the pipeline. To address this issue, we use FEM-simulated, time-reversed signals to focus ultrasound power onto a pre-determined location: a fouled pipe residing inside a Plexiglas container.

Automated image analysis method for oil-release test of lipid-based materials.

We present an automated method to determine oil release from lipid-based materials. Oil-release tests can provide information regarding the ability to retain oil within the structuring network of lipid-based materials. This test provides a first insight into the stability of these materials and their possible applications in food, cosmetic, and pharmaceutical products.

CESAM-Coded excitation scanning acoustic microscope.

Scanning acoustic microscopy (SAM) finds use across many disciplines, e.g., biology, industrial quality control, and materials science, thanks to its unique ability to quantify mechanical sample properties combined with its high resolution.

Defect localization by an extended laser source on a hemisphere.

The primary goal of this study is to localize a defect (cavity) in a curved geometry. Curved topologies exhibit multiple resonances and the presence of hotspots for acoustic waves. Launching acoustic waves along a specific direction e.

Controlling oleogel crystallization using ultrasonic standing waves.

Oleogels are lipid-based soft materials composed of large fractions of oil (> 85%) developed as saturated and hydrogenated fat substitutes to reduce cardiovascular diseases caused by obesity. Promising oleogels are unstable during storage, and to improve their stability careful control of the crystalline network is necessary. However, this is unattainable with state-of-the-art technologies.

Non-contact determination of intra-ocular pressure in an ex vivo porcine model.

People suffering from glaucoma often endure high intra-ocular pressure (IOP). Methods for determining IOP either contact the eye or are unpleasant to some patients. There is therefore a need for a rapid and patient friendly non-contacting method to determine IOP.

Localized delivery of compounds into articular cartilage by using high-intensity focused ultrasound.

Localized delivery of drugs into an osteoarthritic cartilaginous lesion does not yet exist, which limits pharmaceutical management of osteoarthritis (OA). High-intensity focused ultrasound (HIFU) provides a means to actuate matter from a distance in a non-destructive way. In this study, we aimed to deliver methylene blue locally into bovine articular cartilage in vitro.

Comparison of Traditional and Ultrasound-Enhanced Electrospinning in Fabricating Nanofibrous Drug Delivery Systems.

We investigated nozzleless ultrasound-enhanced electrospinning (USES) as means to generate nanofibrous drug delivery systems (DDSs) for pharmaceutical and biomedical applications. Traditional electrospinning (TES) equipped with a conventional spinneret was used as a reference method. High-molecular polyethylene oxide (PEO) and chitosan were used as carrier polymers and theophylline anhydrate as a water-soluble model drug.

Scattering And Absorption of Light in Planetary Regoliths.

Theoretical, numerical, and experimental methods are presented for multiple scattering of light in macroscopic discrete random media of densely-packed microscopic particles. The theoretical and numerical methods constitute a framework of Radiative Transfer with Reciprocal Transactions (RT). The RT framework entails Monte Carlo order-of-scattering tracing of interactions in the frequency space, assuming that the fundamental scatterers and absorbers are wavelength-scale volume elements composed of large numbers of randomly distributed particles.

Practical realization of a sub-λ/2 acoustic jet.

Studies in optics and acoustics have employed metamaterial lenses to achieve sub-wavelength localization, e.g. a recently introduced concept called 'acoustojet' which in simulations localizes acoustic energy to a spot smaller than λ/2.

Ultrasound-enhanced electrospinning.

Electrospinning is commonly used to produce polymeric nanofibers. Potential applications for such fibers include novel drug delivery systems, tissue engineering scaffolds, and filters. Electrospinning, however, has shortcomings such as needle clogging and limited ability to control the fiber-properties in a non-chemical manner.

Laser-ultrasonic delivery of agents into articular cartilage.

Research is ongoing to develop drug therapies to manage osteoarthritis (OA) and articular cartilage (AC) injuries. However, means to deliver drug to localized AC lesions are highly limited and not clinically available. This study investigates the capability of laser ultrasound (laser-induced plasma sound source) to deliver agents (methylene blue, MB, in PBS) into bovine AC.

Effects of acoustic levitation on the development of zebrafish, Danio rerio, embryos.

Acoustic levitation provides potential to characterize and manipulate material such as solid particles and fluid in a wall-less environment. While attempts to levitate small animals have been made, the biological effects of such levitation have been scarcely documented. Here, our goal was to explore if zebrafish embryos can be levitated (peak pressures at the pressure node and anti-node: 135 dB and 144 dB, respectively) with no effects on early development.

Delivering Agents Locally into Articular Cartilage by Intense MHz Ultrasound.

There is no cure for osteoarthritis. Current drug delivery relies on systemic delivery or injections into the joint. Because articular cartilage (AC) degeneration can be local and drug exposure outside the lesion can cause adverse effects, localized drug delivery could permit new drug treatment strategies.

Tailoring the excitation of fundamental flexural guide waves in coated bone by phase-delayed array: two-dimensional simulations.

The fundamental flexural guided wave (FFGW) enables ultrasonic assessment of cortical bone thickness. In vivo, it is challenging to detect this mode, as its power ratio with respect to disturbing ultrasound is reduced by soft tissue covering the bone. A phase-delayed ultrasound source is proposed to tailor the FFGW excitation in order to improve its power ratio.

Step length measurement--theory and simulation for tethered bead constant-force single molecule assay.

Linear molecular motors translocate along polymeric tracks using discrete steps. The step length is usually measured using constant-force single molecule experiments in which the polymer is tethered to a force-clamped microsphere. During the enzymatic cycle the motor shortens the tether contour length.