-glucosidase and -amylase inhibitory activity of flavonols from (Burm.f.) Bedd.

(Burm.f.) Bedd.

Indonesian marine and its medicinal contribution.

The archipelagic country of Indonesia is populated by the densest marine biodiversity in the world which has created strong global interest and is valued by both Indigenous and European settlements for different purposes. Nearly 1000 chemicals have been extracted and identified. In this review, a systematic data curation was employed to collate bioprospecting related manuscripts providing a comprehensive directory based on publications from 1988 to 2022.

Anti-cancer bioprospecting on medicinal plants from Indonesia: A review.

The Indonesian archipelago is home to the second largest biodiversity in the world and is inhabited by more than 300 ethnic groups with a total population of more than 270 million. The indigenous population still rely on traditional medicine practices, especially the use of plant-based remedies. Although modern science-based exploration on Indonesian medicinal plants started with the European settlement in the archipelago in the 16th century, it was not until the 1970's that the phytochemistry of Indonesian medicinal plants was recognized for its potency.

Free Radical Scavenging, Anti-Infectious, and Toxicity Activities from (Burm.f.) Bedd. Extracts.

(Burm.f.) Bedd.

Phytochemistry and Pharmacology of Medicinal Plants Used by the Tenggerese Society in Java Island of Indonesia.

The archipelagic country of Indonesia is inhabited by 300 ethnic groups, including the indigenous people of Tengger. Based on the reported list of medicinal plants used by the Tengger community, we have reviewed each of them for their phytochemical constituents and pharmacological activities. Out of a total of 41 medicinal plants used by the Tengerrese people, 33 species were studied for their phytochemical and pharmacological properties.

Simple monitoring of pH and urea in whole blood using wearable smart woman pad.

In this work, we used a thread-paper microfluidic device (μTPAD) system, where a threaded part for the handling of the whole blood samples and a paper part for the reaction of plasma with immobilized bioreagents integrated into woman pad as a wearable sensing device namely as smart women pad. The μTPAD as a wearable smart woman pad is developed for the detection of pH and urea in mensuration blood as real samples. This combined device was constructed to cover the elements required, that is, separation of red blood cell, conditioning, analyte reaction, and colorimetric detection.

Anti-cancer Evaluation of Depsides Isolated from Indonesian Folious Lichens: , and .

Cancer is a serious health burden on global societies. The discovery and development of new anti-cancer therapies remains a challenging objective. Although it has been shown that lichen secondary metabolites may be potent sources for new anti-cancer agents, the Indonesian- grown folious lichens, and have not yet been explored.

Anthelmintic and antimicrobial activities of three new depsides and ten known depsides and phenols from Indonesian lichen: Ach.

An extensive phytochemical study of a foliose lichen from Indonesia, , resulted in the successful isolation of 13 phenol and depside derivatives (-) including the previously unreported depsides 3'-hydroxyl-5'-pentylphenyl 2,4-dihydroxyl-6-methylbenzoate (), 3'-hydroxyl-5'-propylphenyl 2,4-dihydroxyl-6-methylbenzoate () and 3'-hydroxyl-5'-methylphenyl 2-hydroxyl-4-methoxyl-6-propylbenzoate (). The anti-infective activity of isolated compounds was evaluated against the gram-negative bacterium and the nematode . 2,4-Dihydroxyl-6-pentylbenzoate () and lecanoric acid () induced growth inhibition of with inhibition values of 49% and 100% at a concentration of 100 µM, respectively.

Anti-Infective and Anti-Cancer Properties of the Species: Their Ethnomedicinal Uses, Alkaloid Diversity, and Pharmacological Activities.

species have been a valuable source of anti-infective and anticancer agents. However, only limited evaluations of their alkaloids have been carried out. This review collates and evaluates the biological data from extracts and purified isolates for their anti-infective and anti-cancer activities.

Alkaloids from the root of Indonesian L.

L. has been used traditionally in Indonesia to treat disease. Phytochemical studies on the alkaloid fractions from the root of L.

Antarctic Moss Biflavonoids Show High Antioxidant and Ultraviolet-Screening Activity.

Ceratodon purpureus is a cosmopolitan moss that survives some of the harshest places on Earth: from frozen Antarctica to hot South Australian deserts. In a study on the survival mechanisms of the species, nine compounds were isolated from Australian and Antarctic C. purpureus.

Bioactive glycosides from the African medicinal plant Boerhavia erecta L.

Phytochemical studies of the previously unexplored stem of Boerhavia erecta from Burkina Faso, resulted in the isolation of an unreported glycoside 4, 2,3-dihydroxypropylbenzoate-3-O-β-[4″-methoxy] glucuronide as well as seven known glycosides (1-3, 5-8). The major isolate 5 and 8 indicated a significant inhibition against HIV integrase (IC50 10 and 22 μg/mL, respectively). The extracts and isolates were also tested for anti-malarial activity, but insignificant activity was observed.

Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia.

The larvae of necrophagous fly species are used as forensic tools for the determination of the minimum postmortem interval (PMI). However, any ingested drugs in corpses may affect larval development, thus leading to incorrect estimates of the period of infestation. This study investigated the effects of methamphetamine and its metabolite, p-hydroxymethamphetamine, on the forensically important Australian blowfly Calliphora stygia.

Revealing indigenous Indonesian traditional medicine: anti-infective agents.

Indonesia is rich in medicinal plants which the population has used traditionally from generation to generation for curing diseases. Our interest in the treatment of infectious diseases has lead to the investigation of traditional Indonesian treatments. In this review, we present a comprehensive review of ethnopharmacologically directed screening in Indonesian medicinal plants to search for new anti-viral, antimalarial, anti-bacterial and anti-fungal agents.