Publications by authors named "Argyro Tsakoumagkou"
Article Synopsis
- The free fatty acid receptor 2 (FFA2/GPR43) is linked to short-chain fatty acids and is a potential target for treating metabolic and inflammatory diseases.
- Researchers conducted bioisosteric replacements on the carboxylic acid group of the FFA2 antagonist CATPB, leading to new compounds.
- TUG-2304 emerged as a high-potency antagonist with impressive activity in tests, showing the ability to fully inhibit neutrophil migration and respiratory bursts triggered by propionate.
