Allergic angina syndrome, allergic myocardial infarct or Kounis syndrome: insights on epidemiology, etiology, diagnosis and treatment. A case report by gadolinium anaphylaxis.

Kounis syndrome (KS) was first described in 1991 by Kounis and Zavras and is also known as allergic angina syndrome or allergy myocardial infarction. It is a rare, and frequently undiagnosed syndrome that is characterized by an anaphylactic reaction. Allergens cause massive degranulation of mast cells leading to coronary spasm, microvascular angina, and/or endothelial dysfunction with myocardial infarction.