Publications by authors named "Arezzo A"

Background: Robotic-assisted endoluminal systems are rapidly evolving within the field of minimally invasive surgery. The IDEAL framework (Idea, Development, Exploration, Assessment, and Surveillance) can be used to evaluate novel technologies. This review provides a summary of current and emerging endoluminal systems using the IDEAL framework.

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Background: Level one evidence supports indocyanine green fluorescence angiography (ICGFA) use reducing anastomotic leak rates in colorectal surgery. We surveyed surgeons exploring perceptions and factors affecting its use in daily practice and adoption as routine standard of care.

Methods: Validated electronic survey distributed via the Irish Association of Coloproctology, Royal College of Surgeons in Ireland, European Society of Surgical Oncology, European Association for Endoscopic Surgery, Milan Colorectal Congress and social media.

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Background: Different reconstruction techniques after total mesorectal excision have been described, such as straight coloanal anastomosis, colonic J-pouch, side-to-end anastomosis and transverse coloplasty pouch. Establishing which technique is the best in functional terms is essential to improving a patient's quality of life.

Methods: We compared benefits and harms of different reconstructive techniques.

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Introduction: Altered vascular microcirculation is recognized as a risk factor for anastomotic leakage (AL) in colorectal surgery. However, few studies evaluated its impact on AL using different devices, with heterogeneous results. The present study reported the initial experience measuring gut microcirculatory density and flow with the aid of incidence dark-field (IDF) videomicroscopy (Cytocam, Braedius, Amsterdam, The Netherlands) comparing its operative outcome using a propensity score matching (PSM) model based on age, gender, and Charlson Comorbidity Index (CCI).

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Background: One of the most important surgical steps during thyroidectomy is the safe ligation of vessels. In fact, it is crucial to avoid postoperative bleeding and nerves' injury. The "clamp and tie" technique was first introduced in the 19th century.

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Introduction: Complete mesocolic excision (CME) is widely adopted for its assumed superior oncological outcome. However, it's unclear if all right-sided colon cancer patients benefit from CME. The aim of this systematic review is to investigate whether CME contributes to postoperative outcomes and to determine the surgical indications for CME.

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Introduction: Colorectal cancer remains one of the most common causes of cancer-related mortality worldwide, and lymph node staging is crucial in the diagnostic and therapeutic process. Sentinel lymph nodes are the first involved in this process, but their validity in colorectal surgery has not yet been established. Following the emergence of new imaging instrumentation, some authors have attempted to propose different techniques for lymph node identification.

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Article Synopsis
  • Radical surgery is the most effective treatment for early-stage lung cancer, with video-assisted thoracic surgery (VATS) being a less painful alternative to traditional surgery methods.
  • Current localization techniques for identifying lung cancer are limited, particularly the near-infrared (NIR) indocyanine green (ICG) method, which struggles with deep tissue and lymph node detection.
  • This study tests the effectiveness of Cetuximab-IRDye800CW, a combination of a monoclonal antibody and an advanced NIR dye, in accurately marking lung nodules and lymph nodes during VATS for improved detection outcomes.
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The search for less-invasive approaches led to the birth of endoluminal surgery 40 years ago. The limited dexterity of flexible endoscopic systems generated an interest in the development of robotic platforms to encourage the adoption of surgical-like, bimanual techniques involving manipulation of tissues, thus favoring organ preservation. Nevertheless, the road ahead for endoluminal surgery is still at the beginning.

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Article Synopsis
  • Surgical care in the operating room creates a lot of greenhouse gas emissions, making up a third of healthcare's total emissions.
  • A big study looked at many articles about how gastrointestinal surgery affects the environment to find ways to make it more sustainable.
  • The results showed that using less anesthetic gases and reducing surgical waste can significantly help lessen the impact on the environment, and having special teams to promote these changes is a good idea.
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Article Synopsis
  • Surgeons around the world are interested in making surgery more eco-friendly, so a group was formed to learn more about their thoughts on this topic.
  • They sent out a survey to understand how surgeons feel about being sustainable, how much they know about the carbon footprint of their surgeries, and what changes they are willing to make.
  • The results showed that most surgeons want to help the environment but don’t know much about how their practices affect it; they prefer learning through online resources.
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  • A systematic review and meta-analysis was conducted to compare High Energy Devices (HEDs) with conventional techniques in thyroid surgery, endorsed by the Italian Society of Surgical Endoscopy.
  • The study included adult patients undergoing thyroid or parathyroid surgeries using HEDs, evaluating their effects on various surgical outcomes.
  • Results showed that HEDs significantly reduced operative time compared to conventional methods, analyzing data from 29 randomized controlled trials involving over 3,000 patients.
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Article Synopsis
  • The healthcare system has a big impact on the environment, especially operating rooms, which contribute a lot to carbon emissions.
  • Major organizations and governments are working together to make healthcare more sustainable and reduce its carbon footprint.
  • A new group called the Sustainability in Surgical Practice task force was formed to promote better practices and encourage actions that help both surgery and the environment.
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Introduction: As life expectancy has been increasing, older patients are becoming more central to the healthcare system, leading to more intensive care use and longer hospital stays. Nevertheless, advancements in minimally invasive surgical techniques offer safe and effective options for older patients with colorectal diseases. This study aims to provide comprehensive evidence on the role of minimally invasive surgery in treating colorectal diseases in older patients.

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Background: As the population ages, more older adults are presenting for surgery. Age-related declines in physiological reserve and functional capacity can result in frailty and poor outcomes after surgery. Hence, optimizing perioperative care in older patients is imperative.

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Hospitals in Europe produce approximately 6 million tons of medical waste annually, about one-third of this originating in operating rooms. Most of it is solid waste, which can be recycled if bodily fluids do not contaminate it. Only 2-3% of hospital waste must be disposed of as infectious waste, and this is much lower than the 50-70% of garbage in the biohazard waste stream.

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Surgeons performing robotic-assisted laparoscopic surgery experience physical stress and overuse of shoulder muscles due to sub-optimal arm support during surgery. The objective is to present a novel design and prototype of a dynamic arm support for robotic laparoscopic surgery to evaluate its ergonomics and performance on the AdLap-VR simulation training device. The prototype was designed using the mechanical engineering design process: Technical requirements, concept creation, concept selection, 3D-design and built of the prototype.

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Aims: The identification of the anatomical components of the Calot's Triangle during laparoscopic cholecystectomy (LC) might be challenging and its difficulty may increase when a surgical trainee (ST) is in charge, ultimately allegedly affecting also the incidence of common bile duct injuries (CBDIs). There are various methods to help reach the critical view of safety (CVS): intraoperative cholangiogram (IOC), critical view of safety in white light (CVS-WL) and near-infrared fluorescent cholangiography (NIRF-C). The primary objective was to compare the use of these techniques to obtain the CVS during elective LC performed by ST.

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Background: The rapid adoption of robotics within minimally invasive surgical specialties has also seen an explosion of new technology including multi- and single port, natural orifice transluminal endoscopic surgery (NOTES), endoluminal and "on-demand" platforms. This review aims to evaluate the validation status of current and emerging MIS robotic platforms, using the IDEAL Framework.

Methods: A scoping review exploring robotic minimally invasive surgical devices, technology and systems in use or being developed was performed, including general surgery, gynaecology, urology and cardiothoracics.

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Aim: Treatment pathways for significant rectal polyps differ depending on the underlying pathology, but pre-excision profiling is imperfect. It has been demonstrated that differences in fluorescence perfusion signals following injection of indocyanine green (ICG) can be analysed mathematically and, with the assistance of artificial intelligence (AI), used to classify tumours endoscopically as benign or malignant. This study aims to validate this method of characterization across multiple clinical sites regarding its generalizability, usability and accuracy while developing clinical-grade software to enable it to become a useful method.

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Background: During minimal access surgery, surgical smoke is produced which can potentially be inhaled by the surgical team, leading to several health risks. This smoke can escape from the abdominal cavity into the operating room due to trocar leakage. The trocars and insufflator that are used during surgery influence gas leakage.

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