candidemia and bacterial co-infection in a 3-month-old infant with biliary atresia.

Candidemia caused by rare and uncommon species is becoming more prevalent in pediatric healthcare settings, resulting in significant morbidity and mortality. One such species, , is resistant to fluconazole but highly susceptible to echinocandins. Here, we report the first documented case of candidemia in Iran that occurred in a male infant with biliary atresia who had been hospitalized for 2 months.

A case of COVID-19-associated mucormycosis due to Lichtheimia ramosa.

Background: Mucormycosis is a life-threatening invasive fungal infection in immunocompromised and COVID-19 patients.

Case Report: Here, we report a fatal rhino-orbito-cerebral mucormycosis caused by Lichtheimia ramosa, in a 79-year-old diabetic female. She was initially admitted to the hospital for COVID-19 infection and received broad-spectrum antibiotics and corticosteroids.

A case of conjunctivitis in a neonate admitted to the cardiac heart intensive care unit.

Harmless commensal species, especially uncommon and rare ones may rarely cause a serious infection. is a recently described yeast that is phenotypically indistinguishable from and molecular methods are essential for its identification. We report the first case of conjunctivitis due to obtained from the eye discharge of a 40-day-old girl with congenital heart disease admitted to the cardiac intensive care unit (CICU).

The first case of Wickerhamomyces anomalus fungemia in Iran in an immuneodeficient child, a review on the literature.

The incidence of invasive candidiasis in pediatric patients is increasing and is associated with significant morbidity and mortality. C. pelliculosa has been rarely reported as a human pathogen, however, it has been associated with serious nosocomial infections and clonal outbreaks with poor clinical outcomes in immunocompromised children were reported.

Multiplex size marker (YEAST PLEX) for rapid and accurate identification of pathogenic yeasts.

Background: Multiple yeast species can cause human disease, involving superficial to deep-seated infections. Treatment of these infections depends on the accurate identification of causative agents; however, reliable methods are not available in many laboratories, especially not in resource-limited settings. Here, a new multiplex assay for rapid and low-cost identification of pathogenic yeasts is described.

Candidemia among Hospitalized Pediatric Patients Caused by Several Clonal Lineages of .

is the second most common cause of candidemia in some geographical areas and in children in particular. Yet, the proportion among children varies, for example, from 10.4% in Denmark to 24.

Differentiation of complex species isolated from invasive and non-invasive infections using gene size polymorphism.

Background And Purpose: Taxonomy of is controversial and has changed due to the investigation of the novel species. and are new members of the complex that are currently gaining both clinical and epidemiologic significance. This study aimed to report the prevalence of among the strains isolated from patients using hyphal wall protein 1 () gene size polymorphism.

Antifungal susceptibility, genotyping, resistance mechanism, and clinical profile of Candida tropicalis blood isolates.

Candida tropicalis is one of the major candidaemia agents, associated with the highest mortality rates among Candida species, and developing resistance to azoles. Little is known about the molecular mechanisms of azole resistance, genotypic diversity, and the clinical background of C. tropicalis infections.

Molecular Identification, Genotypic Diversity, Antifungal Susceptibility, and Clinical Outcomes of Infections Caused by Clinically Underrated Yeasts, , and : An Iranian Multicenter Study (2014-2019).

Despite the increasing occurrence of and in clinical settings, little is known about their microbiological and clinical properties. Herein, we conducted a national retrospective study (2014-2019) from multiple centers in Iran. Among the 1,770 isolates collected, we identified 600 species complex isolates.

Species distribution and antifungal susceptibility profile of Candida isolates from blood and other normally sterile foci from pediatric ICU patients in Tehran, Iran.

As data on pediatric invasive candidiasis (IC) and the antifungal susceptibility pattern of associated isolates are scarce in Iran, this study aimed to determine species distribution and antifungal susceptibility profile of Candida species isolated from pediatric patients with suspected or documented IC. A total of 235 yeast strains recovered from normally sterile body fluids of patients admitted at the intensive care units of Children's Medical Centre, Tehran, Iran, were identified using CHROMagar Candida, molecular methods (ITS PCR-RFLP and sequencing), and MALDI-TOF. Susceptibility to amphotericin B, fluconazole, voriconazole, micafungin, and anidulafungin was determined according to the European on Antimicrobial Susceptibility testing reference microdilution method (EUCAST E.

Molecular characterization and antifungal susceptibility testing of Candida nivariensis from blood samples - an Iranian multicentre study and a review of the literature.

Purpose: Identification of the emerging yeast species Candida nivariensis among presumptively identified Iranian Candida glabrata isolates.

Methodology: Clinical C. glabrata species complex isolates from blood (n=71; 33.

Study on the relationship between the concentration and type of fungal bio-aerosols at indoor and outdoor air in the Children's Medical Center, Tehran, Iran.

Fungal bio-aerosols are of concern due to their adverse health effects, especially in indoor environments. The aim of this study was to evaluate the relationship between the concentration and type of fungal bio-aerosols in the indoor and outdoor of Children's Medical Center in Tehran, Iran. In the present descriptive-analytical study, the fungal bio-aerosols' concentrations in both indoor and outdoor of the hospital air were measured.