Publications by authors named "Arena R"

The Roundtable on Obesity Solutions (ROOS), established in 2014, is a unique organization of multisectoral voices addressing the public health challenge of obesity. The ROOS brings together practitioners, researchers, funders, companies, health systems, government agencies, and the lived experience to dialogue and guide the national conversation about the multilevel challenges and opportunities related to obesity. This paper presents insights and key learnings from a symposium developed to celebrating the 10th Anniversary of the ROOS.

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Aims: To better characterize functional consequences of the presence of COPD on cardiorespiratory fitness in patients with HF.

Methods And Results: Patients with any clinical indication for cardiopulmonary exercise testing (CPET) were included in the international FRIEND registry. Diagnosis of COPD was confirmed by a ratio of forced expiratory volume in 1 s and forced vital capacity (FEV/FVC) < 0.

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Background: Indexing peak oxygen uptake (VOpeak) to total body mass can underestimate cardiorespiratory fitness (CRF) in women, older adults, and individuals with obesity. The primary objective of this multicenter study was to derive and validate a body size-independent scaling metric for VOpeak. This metric was termed exercise body mass (EBM).

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The prevalence of obesity in the United States (U.S.), in conjunction with the myriad of detrimental health consequences associated with this disease, justifiably warrants deep concern and characterization as a national health crisis of epidemic proportions.

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  • - The study investigates the link between social vulnerability and levels of no leisure time physical activity (NO-LTPA) across different U.S. regions over time, highlighting NO-LTPA as a significant contributor to health issues.
  • - Results show higher NO-LTPA rates in certain culturally distinct regions and reveal that 37% of U.S. counties experienced a decrease in NO-LTPA from 2020 to 2022, while many others saw no change or an increase.
  • - The findings suggest a relationship where improvements in social vulnerability could potentially lead to reductions in NO-LTPA, indicating a need for targeted interventions in socially vulnerable areas.
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  • Health indices in the U.S. show significant regional disparities, with certain areas experiencing high rates of unhealthy behaviors and chronic diseases, including arthritis.
  • A study analyzed data from 3,073 counties and found strong correlations between arthritis prevalence and factors like lifestyle health, depression, disability, and social vulnerability.
  • The research highlights the need for a more integrated and proactive approach to health care, moving away from condition-specific treatment to a more holistic model.
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  • The study examined the link between Personal Activity Intelligence (PAI) scores and coronary heart disease (CHD) in a large group of healthy adults in Norway, emphasizing the impact of physical activity intensity on CHD risk.
  • Researchers analyzed data from over 40,000 participants, finding that those with higher PAI scores (51-99 and ≥ 100) had a significantly lower risk of experiencing fatal and non-fatal CHD during a median follow-up of 13.1 years.
  • The inclusion of PAI in traditional risk assessments improved the ability to classify individuals' CHD risk, highlighting that a PAI score above 50 is notably protective against CHD.
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Measures reflecting cardiac sympathovagal activity, particularly those associated with heart rate variability (HRV), are widely recognized and utilized in both scientific and clinical contexts. This study aimed to assess the inter- and intra-examiner reliability of short-term HRV parameters in patients hospitalized with coronavirus disease 2019 (COVID-19). A total of 103 patients (both sexes) diagnosed with COVID-19 were included in the study.

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Aim: We sought the cardiopulmonary exercise testing (CPET) parameter that most accurately reflected therapeutic efficacy in patients with hypertrophic cardiomyopathy (HCM).

Methods: Well-being questionnaire, N-terminal brain natriuretic peptide measurements, echocardiography, and CPET were performed in patients with symptomatic non-obstructive HCM during phase II, randomized, open-label multicentre study, before and after 16 weeks of traditional or sacubitril/valsartan treatment. Patients were followed 36 months after the initial CPET.

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  • Atrial fibrillation (AF) is a widespread health issue, and guidelines recommend weight loss for patients with AF who are also obese, yet few cardiac rehabilitation (CR) programs focus on this need.
  • This randomized controlled trial (RCT) aims to assess whether a "Small Changes" behavioral weight loss treatment (BWLT) alongside CR can help patients with AF and obesity achieve at least 10% weight loss and improve related health outcomes.
  • Participants will be divided into two groups: one receiving CR plus BWLT and the other receiving CR only, with assessments for weight and AF symptoms conducted at multiple points over a year to evaluate the treatment's effectiveness.
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  • * A philosophical inquiry was conducted, exploring key questions about the relationship between humans and AI, trust issues, ethical concerns, and control of AI in health contexts.
  • * The resulting 11 recommendations emphasize a human-centric approach, suggesting workforce planning that incorporates AI and the importance of reporting serious AI-related incidents to regulatory authorities.
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  • Major advancements in medical and surgical treatment for cardiovascular disease (CVD) over the past century have led to improved survival rates and shorter hospital stays, increasing the need for ongoing cardiovascular risk management.
  • Despite these advancements, post-discharge care often relies on outdated rehabilitation models that don't adequately address the long-term needs of survivors living with CVD.
  • The paper advocates for reframing cardiac rehabilitation into a broader concept of supporting cardiovascular health through the "5 P's": personalization, processes, patient-centered care, parlance, and partnership, to better engage survivors and improve their outcomes.
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Background: The Duke Activity Status Index (DASI) questionnaire has been the focus of numerous investigations - its discriminative and prognostic capacity has been continuously explored, supporting its use in the clinical setting, specifically during rehabilitation in patients with chronic heart failure (CHF).However, studies exploring optimal DASI questionnaire threshold scores are limited.

Objective: To investigate optimal DASI questionnaire thresholds values in predicting mortality in a CHF cohort and assess mortality rates based on the DASI questionnaire using a thresholds values obtained.

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The blue crab (), originally from the western Atlantic Ocean, has recently spread to the Mediterranean and is now considered one of the one hundred most invasive species in that region. This opportunistic species, known for its adaptability to different temperatures and salinities, negatively impacts biodiversity and human activities such as fishing and tourism in the Mediterranean. However, the blue crab is gaining interest as a potential food resource due to its high nutritional value and delicate, sweet flavor.

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Objective: This study aimed to test the efficacy of a mHealth-based workplace health promotion strategy in improving cardiorespiratory fitness in a healthcare setting.

Methods: Seventy-seven female nurses (age, 30-45 years) meeting the inclusion criteria underwent baseline assessment and received either a 12-week mHealth or awareness intervention based on their workplace. Changes in peak oxygen consumption (VO 2 ), fasting blood sugar, and physical activity were compared within and between the groups at the end of the intervention.

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Importance: A multicenter randomized clinical trial (RCT) showed a lung recruitment maneuver using high-frequency oscillatory ventilation just before surfactant administration (ie, intubate-recruit-surfactant-extubate [IN-REC-SUR-E]) improved the efficacy of treatment compared with the standard intubate-surfactant-extubate (IN-SUR-E) technique without increasing the risk of adverse neonatal outcomes.

Objective: To examine follow-up outcomes at corrected postnatal age (cPNA) 2 years of preterm infants previously enrolled in an RCT and treated with IN-REC-SUR-E or IN-SUR-E in 35 tertiary neonatal intensive care units.

Design, Setting, And Participants: This was a follow-up study of infants recruited into the primary RCT from 2015 to 2018 at 35 tertiary neonatal intensive care units (NICUs) in Italy.

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Objectives: There are numerous population health challenges confronting the United States (U.S.), including the unhealthy lifestyle - chronic disease pandemics.

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Article Synopsis
  • - The study investigates how general health, social factors, and behaviors at the county level affect oral health indicators, examining differences across various regional cultures in the U.S. based on the American Nations model.
  • - Researchers created a Lifestyle Health Index (LHI) from new data sources and found strong correlations between LHI, social vulnerability, and dental health measures, revealing significant disparities in dental visits and tooth loss across different cultural regions.
  • - The findings suggest that oral health is influenced by lifestyle, social conditions, and cultural beliefs, emphasizing the need for tailored health communications and policies that take regional cultural differences into account to enhance dental care and outcomes.
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Aim: Poor cardiorespiratory fitness has been suggested to increase the risk of chronic diseases in obesity. We investigated the ability of key variables from cardiopulmonary exercise testing (CPET) to predict all-cause mortality in an obese cohort.

Methods: The sample included 469 participants of both sexes (mean age 40 ± 13 years) who underwent a CPET for clinical reasons between 1 March 2009 and 1 December 2023.

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Fast and sensitive quantification of drugs as emerging pollutants in water bodies is a pressing need in contemporary society, to prevent serious environmental concerns that could negatively impact on human health. This explains the surge of interest in this field, and the need to identify highly selective sensing systems. Addressing this issue, in this work we synthesized two D-glucamine functionalized fluorophores bearing self-assembling cores, as 1,8-naphthalimide and naphthalene diimide.

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Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context. Haemodynamic stress promotes alveolar and vascular derangement with loss of functional units, impaired lung capillary permeability and fluid swelling.

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