Publications by authors named "Arega Gashaw"

Spinal schistosomiasis, a rare manifestation of schistosomal infection, can closely mimic the presentation of spinal cord tumors and pose significant diagnostic challenges. We present the case of a 12-year-old boy from northern Ethiopia who experienced progressive back pain, tingling sensations in his lower extremities, and intermittent fever. Initially referred with a presumptive diagnosis of myxopapillary ependymoma for pediatric hematology-oncology evaluation, his marked eosinophilia and history of swimming in local rivers raised suspicion for spinal schistosomiasis.

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Rhabdomyoma is a rare benign tumor of striated muscle, which can be either cardiac or extracardiac. Extracardiac rhabdomyomas can occur throughout the body, though the fetal and adult subtypes are most commonly found in the head and neck region.We present three pediatric cases of extracardiac rhabdomyoma, fetal subtype, detailing their clinical presentations, computed tomography imaging, and tissue biopsy findings.

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Primary intracranial yolk sac tumor (YST) with orbital involvement is an exceedingly rare extragonadal germ cell tumor, with only a limited number of cases reported in the literature. Clinically, primary intracranial yolk sac tumor with orbital involvement may present with symptoms that mimic more common benign or malignant orbital disorders in children, potentially leading to diagnostic delays that can adversely impact survival. Diagnostic imaging modalities, including computed tomography (CT) and magnetic resonance imaging (MRI), are instrumental for assessing the tumor's size, precise localization, and extent.

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Most newly diagnosed pediatric cancer patients reside in LMICs. These countries face challenges in providing quality treatment, particularly with procedures requiring stillness or causing pain. Conscious sedation (CS) is underutilized in LMICs due, causing treatment delays and adverse outcomes.

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. Many caregivers who care for their children with cancer are affected by the care burden due to the chronic nature of the disease. This study aimed to determine the burden of care level and its related factors in the caregivers of children with cancer.

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Background: Pediatric Acute Myeloid Leukemia (AML) is a major cause of morbidity and mortality in children with cancer in Africa and other developing continents. Systemic chemotherapy and effective supportive care have significantly contributed to increased survival rates of pediatric AML in developed countries reaching approximately 70%. There is a paucity of contextual data regarding overall and event-free survival outcomes in children with acute myeloid leukemia in developing countries and most centers in Africa provide palliative care.

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Background: Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall survival of children with primary malignant bone tumors is affected by the stage of disease, time of diagnosis, and treatment response.

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In tuberculous patient, abnormal extrarenal production of 1.25-dihydroxyvitamin D3 by activated macrophages results in hypercalcemia. High calcium level associated with tuberculosis is frequent in adults with active pulmonary tuberculosis even though most patients are asymptomatic, while hypercalcemia in children due to disseminated tuberculosis is rare.

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Article Synopsis
  • Liver masses are a significant health issue in children, particularly in developing countries, where limited studies exist to understand their patterns and characteristics.
  • A study analyzed 74 children, mainly males aged around 4.6 years, showing that most commonly they presented with abdominal swelling, with benign masses being more prevalent than malignant ones.
  • Pyogenic liver abscesses and hepatoblastomas were identified as the most common benign and malignant lesions, respectively, highlighting the need for better understanding and early diagnosis to improve outcomes.
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Leukoerythroblastosis is rarely encountered in clinical practice and is characterized by the presence of leukocytosis and erythroid and myeloid blast cells in peripheral blood. The most common causes of leukoerythroblastosis in early childhood are viral infection, juvenile myelomonocytic leukemia, and osteopetrosis. To the best of our knowledge, leukoerythroblastic reactions associated with hemolysis have not been previously reported in newborns.

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Hydatid cyst is a zoonotic disease caused by CestodaEchinococcus, especially Echinococcus granulosus. Isolated renal hydatidosis is an extremely rare clinical condition associated with nonspecific symptoms and physical findings. Diagnosis can be difficult and depends on imaging findings and histologic examination of excised tissue specimens.

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Laryngeal leech infestation is a rare cause of upper air way obstruction in children. A high index of clinical suspicion of laryngeal leech infestation has to made in child presented with foreign body sensation in the aerodigestive tract, symptoms and signs suggestive of upper air way obstruction especially in areas where drinking water from the streams and ponds is a habit. Here, we report a 9-year-old male child who presented with signs of upper air way obstruction: coughing, shortness of breath, stridor and use of accessory muscles.

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Article Synopsis
  • Hydatidosis is a parasitic disease that primarily impacts children, often targeting the lungs and liver, but brain involvement is rare.
  • An 8-year-old girl was diagnosed with a brain hydatid cyst after imaging showed a cystic lesion in the temporoparietal lobe, leading to surgery for its removal.
  • Post-surgery, the cyst was confirmed through histopathology, and the patient recovered well, beginning albendazole therapy before discharge.
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Hydatidosis is a parasitic disease caused by , which is endemic in many parts of the world. Hydatid cysts can occur in any organ of the human body and the lung is the most common site in children, primarily related to higher lung tissue elasticity. Bilateral pulmonary hydatid cyst is a rare clinical phenomenon in young children.

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Background: Judicious utilization of drugs rescues the fetus from the harmful effects while treating the health problems of the pregnant women. This study aimed at evaluating drug utilization pattern and its associated factors among pregnant women in Southern Tigray, Ethiopia.

Method: Institution based cross-sectional study was conducted among 647 pregnant women who had been attending obstetrics-gynecology and antenatal care units in different health facilities of Southern Tigray region.

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Application of N-2-(chloro-4-pyridyl)-N-phenyl urea (CPPU) to salt susceptible cultivar of indica rice (cv. PTT1) effected on free proline and soluble sugar accumulation and regulated the physio-morphological responses when subjected to salt stress condition was firstly demonstrated in this study. Soluble sugars, including sucrose, glucose and fructose, in leaf blade and leaf sheath were enriched in 0.

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