Publications by authors named "Arefeh Shahriary"
Akkermansia muciniphila, as a member of the gut microbiota, has been proposed as a next-generation probiotic. Liver fibrosis is the main determinant of liver dysfunction and mortality in patients with chronic liver disease. In this study, we aimed to determine the beneficial effects of live and pasteurized A.
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- Probiotics can help improve gut health and metabolism related to obesity by altering the gut microbiota and maintaining mucosal barrier integrity.
- The study examined the effects of probiotics and their extracellular vesicles (EVs) on obesity-related genes using assays in both cell lines and C57BL/6 mice.
- Results indicated that EVs were more effective than the probiotics alone in reducing body and fat weight, enhancing lipid metabolism, and improving inflammation markers and blood parameters in high-fat diet-fed mice.
Comparative study of effect of and its extracellular vesicles on toll-like receptors and tight junction.
Gastroenterol Hepatol Bed Bench
January 2019
Aim: We assessed effect of and its extracellular vesicles on toll-like receptors and tight junction expression in human epithelial colorectal adenocarcinoma cells (Caco-2).
Background: The intestinal microbiota plays an important role in the intestinal homeostasis through its metabolites and derivatives. Interacting with immune cells and intestinal epithelial pattern recognition receptors (PRRs), intestinal microbiota regulates the function of the digestive barrier and inflammation caused by the metabolic diseases.