Violence Against Healthcare Workers at Primary Care Centers in Dammam and Al Khobar, Eastern Province, Saudi Arabia, 2019.

Purpose: Workplace violence is common throughout the world. It causes many serious problems in the healthcare sector, where it significantly impacts healthcare workers, the services provided, and organizations as a whole. However, few studies have investigated these issues in Saudi Arabia.

Association between polymorphisms and XELIRI and XELOX chemoresistance in Saudi patients with colorectal cancer.

Multidrug resistance member 1 (MDR1) is located on chromosome 7 and encodes P-glycoprotein, which is universally accepted as a drug resistance biomarker. polymorphisms can alter protein expression or function, which has been previously reported to associate with various types of malignancies, such as colorectal cancer (CRC). Therefore, the present study aimed to determine the effects of polymorphisms on drug responses of Saudi patients with CRC.

variants C3435T and T129C are not associated with colorectal cancer risk.

Background: Colorectal cancer (CRC) is one of the most prevalent cancers in Saudi Arabia that is highly characterized with poor survival rate and advanced metastasis. Many studies contribute this poor outcome to the expression of ABC transporters on the surface of cancer cells.

Objectives: In this study, two variants, C3435T and T129C, were examined to evaluate their contribution to CRC risk.