Publications by authors named "Areej Fatima"

Article Synopsis
  • Giant cell tumour of bone (GCTB) is a rare benign tumor that mainly affects young adults (ages 20-40) and is classified as an intermediate malignant tumor by the WHO, with its pathology linked to the expression of RANKL.
  • A study conducted over 36 months at a military hospital investigated the effects of preoperative denosumab therapy on GCTB patients, measuring pain and functional status before and after treatment.
  • Results showed significant improvement in pain and function, shifting the intended surgical approach from more invasive procedures like joint resection to less aggressive options such as intralesional curettage post-denosumab therapy.
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Emerging Industry 5.0 designs promote artificial intelligence services and data-driven applications across multiple places with varying ownership that need special data protection and privacy considerations to prevent the disclosure of private information to outsiders. Due to this, federated learning offers a method for improving machine-learning models without accessing the train data at a single manufacturing facility.

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This study employs a novel fuzzy logic-based framework to address multi-attribute group decision-making problems commonly encountered in modern astronomy. Our approach utilizes the probabilistic linguistic -rung orthopair fuzzy set (PL-ROFS) to handle the inherent uncertainties associated with astronomical data. The PL-ROFS offers significant advantages over existing fuzzy sets like probabilistic hesitant, linguistic intuitionistic, and linguistic Pythagorean fuzzy sets, which comprise both stochastic and non-stochastic uncertainties simultaneously.

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Article Synopsis
  • The study analyzed the effectiveness of anteromedial cortical support in preventing mechanical complications in unstable pertrochanteric fractures treated with cephalomedullary nails.
  • Conducted over 24 months at a military hospital, the study included 202 patients, and 132 completed follow-up assessments after accounting for mortality and loss to follow-up.
  • Results showed that 9.09% of patients developed complications, with specific criteria indicating a significant relationship between fracture reduction quality and mechanical issues in the post-operative period.
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A strategy of complete revascularization (CR) is recommended in patients with acute coronary syndrome (ACS) and multivessel disease (MVD). However, the optimal timing of CR remains equivocal. We searched MEDLINE, Embase, the Cochrane Library, and ClinicalTrials.

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In response to Chen et al.'s comments on our paper regarding the significance of anti-COVID-IgA antibody response in COVID-19 breakthrough infection in vaccinated patients, we have highlighted the role and the scope of this paper in this correspondence. The role of anti-COVID-19-IgA is already known.

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An increasing number of breakthrough-COVID-19-vaccinated individuals are being reported across the world. Humoral immunity has a crucial role in combating infection. In this study, we aimed to assess the importance of anti-COVID-S1-IgA and anti-COVID-NP-IgA in confirmed COVID-19 after vaccination (breakthrough infection group).

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The benefits of large-scale genetic studies for healthcare of the populations studied are well documented, but these genetic studies have traditionally ignored people from some parts of the world, such as South Asia. Here we describe whole genome sequence (WGS) data from 4806 individuals recruited from the healthcare delivery systems of Pakistan, India and Bangladesh, combined with WGS from 927 individuals from isolated South Asian populations. We characterize population structure in South Asia and describe a genotyping array (SARGAM) and imputation reference panel that are optimized for South Asian genomes.

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It is estimated that viral infections contribute 15-20% of all human cancers. Several types of human papillomaviruse (HPV) are related to the development of many cancer types and their treatment. About 200 HPV viruses have been identified, and each type of virus is integrated with a certain type of clinical lesions affecting the areas of skin and mucous membranes.

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Currently approved therapies for COVID-19 are mostly limited by their low availability, high costs or the requirement of parenteral administration by trained medical personnel in an in-hospital setting. Quercetin is a cheap and easily accessible therapeutic option for COVID-19 patients. However, it has not been evaluated in a systematic review until now.

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COVID-19 is a rapidly spreading pandemic, and early detection is important to halting the spread of infection. Recently, the outbreak of this virus has severely affected people around the world with increasing death rates. The increased death rates are because of its spreading nature among people, mainly through physical interactions.

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The diagnosis of systemic autoimmune diseases (SAID) is challenging, due to overlapping features with other non-immune disorders. Anti-nuclear antibodies (ANA)/anti-cellular antibodies are the sensitive screening tests but anti-double-stranded-deoxyribonucleic acid-antibody (anti-ds-DNA) and ANA-specific antibodies are specific for SAID. We aimed to look at ANA-specific antibodies in our patients and correlated them with ANA patterns, anti-ds-DNA, and clinical diagnosis for proper interpretation and better patient management cost-effectively.

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Bisphenol S (BPS) is an analog of bisphenol A, which is used as substitute of BPA in many products like airport luggage tags, baby bottles, plastics, and epoxy resins etc. Bisphenol S can cause toxic effects in different organisms, i.e.

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The Internet of Medical Things (IoMT) enables digital devices to gather, infer, and broadcast health data via the cloud platform. The phenomenal growth of the IoMT is fueled by many factors, including the widespread and growing availability of wearables and the ever-decreasing cost of sensor-based technology. The cost of related healthcare will rise as the global population of elderly people grows in parallel with an overall life expectancy that demands affordable healthcare services, solutions, and developments.

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Purpose: The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we investigated whether copy number information of MammaPrint™ genes at the DNA level can be used as a prognostic tool for breast cancer, as copy number variations (CNVs) are major contributors to cancer progression.

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