Publications by authors named "Ardin Ouayoue"
Immediately after invading their chosen host cell, the mature human erythrocyte, malaria parasites begin to export an array of proteins to this compartment, where they initiate processes that are prerequisite for parasite survival and propagation, including nutrient import and immune evasion. One consequence of these activities is the emergence of novel adhesive phenotypes that can lead directly to pathology in the human host. To identify parasite proteins involved in this process, we used modern genetic tools to target genes encoding 15 exported parasite proteins, selected by an in silico workflow.
View Article and Find Full Text PDFArticle Synopsis
- Researchers are exploring noninvasive methods for malaria detection, particularly using saliva samples instead of blood, as the current methods are costly and pose health risks.
- A study conducted in Cameroon involved 100 participants and compared various diagnostic techniques like rapid tests, microscopy, PCR, and LAMP, measuring their accuracy for detecting malaria in both blood and saliva samples.
- Results indicated that while both blood and saliva tests had relatively low sensitivity, saliva-based tests, especially the LAMP method, showed promise and could be beneficial for malaria diagnosis in resource-limited settings after further validation.