Age-related testosterone decline in a Brazilian cohort of healthy military men.

Introduction: Androgen decline in the aging man has become a topic of increasing clinical relevance worldwide, as the reduction in testosterone levels has been reported to be accompanied by loss of muscle mass, accumulation of central adiposity, impaired mobility and increase risk of bone fractures. Although well-established in studies conducted in developed countries, progressive decline in serum testosterone levels with age has been poorly investigated in Brazil.

Aim: To determine the pattern of blood testosterone concentrations decline with age in a cohort of Brazilian healthy military men.

Efficacy and tolerability of lodenafil carbonate for oral therapy in erectile dysfunction: a phase II clinical trial.

Introduction: Oral treatment with phosphodiesterase type 5 inhibitor (PDE5) is considered the first-line treatment for patients with erectile dysfunction (ED). Lodenafil carbonate (LC) is a novel PDE5.

Aim: This is a phase II, prospective, randomized, double-blind, and placebo controlled clinical trial of LC.