A label-free DNAzyme-based colorimetric sensor for the detection of Leptospira interrogans.

Leptospirosis is a neglected zoonosis caused by a pathogenic spirochete Leptospira. Diagnosis of leptospirosis in the early stage is difficult and can be easily confused with other infections. The existing detection methods are considered chronophagous and labor-intensive.

Aptamer-based assay for rapid detection, surveillance, and screening of pathogenic Leptospira in water samples.

Leptospirosis is a potentially fatal waterborne infection caused by Leptospira interrogans, impacting both humans and animals in tropical regions. However, current diagnostic methods for detecting pathogenic Leptospira have sensitivity, cost, and time limitations. Therefore, there is a critical need for a rapid, sensitive, and cost-effective detection method.

Assessment of the growth inhibition and anti-biofilm activity of aptamer (PmA2G02) against Proteus mirabilis 1429.

Proteus mirabilis is known to cause Catheter-associated urinary tract infections (CAUTIs), which exhibit virulence factors linked to forming biofilms. Aptamers have recently been explored as potential anti-biofilm agents. This study demonstrates the anti-biofilm activity of aptamer (PmA2G02) targeting P.

Biofilm formation and social interaction of Leptospira in natural and artificial environments.

In the recent decades, there has been increased interest in the study on social interactions of pathogenic bacteria and biofilm-forming microbes. Leptospira is a zoonotic pathogen that causes human leptospirosis. Biofilm formation by pathogenic and saprophytic Leptospira has been documented in various biotic and abiotic environments.

Aptamer-based approaches for the detection of waterborne pathogens.

Waterborne ailments pose a serious threat to public health and are a huge economic burden. Lack of hygiene in drinking and recreational water is the chief source of microbial pathogens in developing countries. Poor water quality and sanitation account for more than 3.

Small-RNA analysis of pre-basic mother plants and conserved accessions of plant genetic resources for the presence of viruses.

Pathogen-free stocks of vegetatively propagated plants are crucial in certified plant production. They require regular monitoring of the plant germplasm for pathogens, especially of the stocks maintained in the field. Here we tested pre-basic mother plants of Fragaria, Rubus and Ribes spp.