Publications by authors named "Aravind S Pillai"

Article Synopsis
  • - The study investigates highly pathogenic avian influenza (HPAI) H5N1 viruses in Indian poultry, particularly focusing on the clade 2.3.2.1, which has been prevalent since 2011 and differs antigenically from other clades like 2.2.
  • - Researchers characterized 11 selected H5N1 viruses using antigenic cartography and phylogenetic analysis to identify differences between and within the clades, emphasizing the variability and potential implications for vaccine development.
  • - The analysis included the glycosylation patterns of Hemagglutinin (HA) and growth kinetics in cell cultures, discovering that some viruses exhibit better replication, which may inform future strategies in creating effective H5 vaccine
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The infectious bronchitis virus is a causative agent of avian infectious bronchitis (AIB), and is is an important disease that produces severe economic losses to the poultry industry worldwide. Recent AIB outbreaks in India have been associated with poor growth in broilers, drop in egg production, and thin egg shells in layers. The complete spike gene of Indian AIB vaccine strain was amplified and sequenced using a conventional reverse transcription polymerase chain reaction and is submitted to the GenBank (accession no KF188436).

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Avian infectious bronchitis is ubiquitous and highly contagious disease of poultry, with profound effect on commercial poultry production. For effective control of infectious bronchitis virus (IBV), quick and specific diagnosis is of utmost importance. In this study, the virus was isolated from clinical samples from India and the full length nucleocapsid (N) gene was amplified, cloned and expressed in a prokaryotic system.

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