Bio-macromolecular design roadmap towards tough bioadhesives.

Emerging sutureless wound-closure techniques have led to paradigm shifts in wound management. State-of-the-art biomaterials offer biocompatible and biodegradable platforms enabling high cohesion (toughness) and adhesion for rapid bleeding control as well as robust attachment of implantable devices. Tough bioadhesion stems from the synergistic contributions of cohesive and adhesive interactions.

Comprehensive review of conventional and state-of-the-art detection methods of Cryptosporidium.

Cryptosporidium is a critical waterborne protozoan pathogen found in water resources that have been a major cause of death and serious illnesses worldwide, costing millions of dollars annually for its detection and treatment. Over the past several decades, substantial efforts have been made towards developing techniques for the detection of Cryptosporidium. Early diagnostic techniques were established based on the existing tools in laboratories, such as microscopes.

Micron-sized particle separation with standing surface acoustic wave-Experimental and numerical approaches.

Traditional cell/particle isolation methods are time-consuming and expensive and can lead to morphology disruptions due to high induced shear stress. To address these problems, novel lab-on-a-chip-based purification methods have been employed. Among various methods introduced for the separation and purification of cells and synthetics particles, acoustofluidics has been one of the most effective methods.

Sheath-assisted versus sheathless dielectrophoretic particle separation.

Lab-on-chip devices are widely being used for binary and ternary cell/particle separation applications. Among the lab-on-chip methods, dielectrophoresis (DEP) is a cost-effective and label-free method, with great capabilities for size-based separation of cells and particles, which is mostly performed in sheath-assisted forms. However, the elimination of the sheath flows offers advantages such as ease of operation and higher sample throughput.

Sheath-assisted focusing of microparticles on lab-on-a-chip platforms.

Lab-on-a-chip (LOC) technologies can take advantage of sheath flows for particle/cell focusing before sensing or sorting. The integration of focusing with other microscale manipulation techniques (e.g.

Parametric study on the geometrical parameters of a lab-on-a-chip platform with tilted planar electrodes for continuous dielectrophoretic manipulation of microparticles.

Advances in lab-on-a-chip (LOC) devices have led to significant improvements in the on-chip manipulation, separation, sorting, and isolation of particles and cells. Among various LOC-based approaches such as inertia-based methods, acoustophoresis, and magnetophoresis, the planar-slanted-electrode dielectrophoresis (DEP) method has demonstrated great potential as a label-free, cost-effective, and user-friendly approach. However, the devices built based on this method suffer from low flow throughput compared to devices functioning based on other LOC-based manipulation approaches.

Graphene/poly (methyl methacrylate) electrochemical impedance-transduced chemiresistor for detection of volatile organic compounds in aqueous medium.

In this paper, an impedance-transduced sensor is developed based on a nanostructured graphene (GN) and poly (methyl methacrylate) (PMMA) sensing film for the detection of individual volatile organic compounds (VOCs) in aqueous media. Benefiting from a porous and high surface area, the nanostructured nanofiber is characterized by scanning electron microscopy (SEM) and optimized by the electrochemical impedance spectroscopy (EIS) technique. The recorded EIS data indicate the selective recognition of four VOCs of interest at a constant pH while there is no redox probe.

Graphene-Coated Spandex Sensors Embedded into Silicone Sheath for Composites Health Monitoring and Wearable Applications.

This study presents a low-cost, tunable, and stretchable sensor fabricated based on spandex (SpX) yarns coated with graphene nanoplatelets (GnP) through a dip-coating process. The SpX/GnP is wrapped into a stretchable silicone rubber (SR) sheath to protect the conductive layer against harsh conditions, which allows for fabricating washable wearable sensors. Dip-coating parameters are optimized to obtain the maximum GnP coating rate.

A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches.

Several biomedical analyses are performed on particular types of cells present in body samples or using functionalized microparticles. Success in such analyses depends on the ability to separate or isolate the target cells or microparticles from the rest of the sample. In conventional procedures, multiple pieces of equipment, such as centrifuges, magnets, and macroscale filters, are used for such purposes, which are time-consuming, associated with human error, and require several operational steps.