Publications by authors named "Arantxa Medina Baez"
Background: Although emerging data during the SARS-CoV-2 pandemic have demonstrated robust messenger RNA vaccine-induced immunogenicity across populations, including pregnant and lactating individuals, the rapid waning of vaccine-induced immunity and the emergence of variants of concern motivated the use of messenger RNA vaccine booster doses. Whether all populations, including pregnant and lactating individuals, will mount a comparable response to a booster dose is not known.
Objective: This study aimed to profile the humoral immune response to a COVID-19 messenger RNA booster dose in a cohort of pregnant, lactating, and nonpregnant age-matched women.
Article Synopsis
- The study investigates the effects of three different COVID-19 vaccines on the immune response in both pregnant individuals and their newborns.
- Findings show that mRNA vaccines (mRNA-1273 and BNT162b2) produce better antibody responses compared to the Ad26.COV2.S vaccine, with mRNA-1273 performing slightly better than BNT162b2.
- Vaccination in the first and third trimesters boosts maternal immune responses and improves antibody transfer to the baby, suggesting that the timing of vaccination plays a crucial role in immunity.