Publications by authors named "Arantxa Cardona Barberan"

Article Synopsis
  • * Previous research has linked certain genetic variants to fertilization issues in ICSI, highlighting the need for larger studies to gauge how often these variants appear and their impact on calcium release during oocyte activation.
  • * The study involved two cohorts where genetic screenings were performed, with one group receiving comprehensive screening and both groups having low previous fertilization rates; they tested a technique to better activate oocytes and hopefully
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Purpose: Providing additional insights on the efficacy of human nuclear transfer (NT). Here, and earlier, NT has been applied to minimize transmission risk of mitochondrial DNA (mtDNA) diseases. NT has also been proposed for treating infertility, but it is still unclear which infertility indications would benefit.

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Infertility affects approximately 15% of reproductive-aged couples worldwide, of which up to 30% of the cases are caused by male factors alone. The origin of male infertility is mostly attributed to sperm abnormalities, of which many are caused by genetic defects. The development of intracytoplasmic sperm injection (ICSI) has helped to circumvent most male infertility conditions.

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