Effectiveness and Complications of the AMS AdVance™ Male Sling System for the Treatment of Stress Urinary Incontinence: A Prospective Multicenter Study.

Objective: To evaluate the effectiveness and tolerance of the AdVance Male Sling System for the treatment of male stress urinary incontinence in patients after prostatic surgery.

Methods: An international, observational, prospective, multicenter study was conducted on male patients with urinary incontinence after prostatic surgery. Patients underwent a 24-hour pad test with a threshold at 250 g.

Pelvic Organ Prolapse Repair with Mesh: Mid-Term Efficacy and Complications.

Introduction: Our aim was to assess the efficacy and complications of pelvic organ prolapse (POP) correction with transvaginal mesh (TVM).

Materials And Methods: We retrospectively assessed patients who had undergone a repair of an apical (primary or recurrent) or recurrent POP using TVM in our department since 2007. Meshes used were Prolift®, Elevate®, and Surelift®.

A re-adjustable sling for female recurrent stress incontinence and sphincteric deficiency: Outcomes and complications in 125 patients using the Remeex sling system.

Aims: To evaluate the outcomes, complications, and quality of life of patients after a Remeex re-adjustable sling for recurrent stress urinary incontinence (SUI) and intrinsic sphincteric deficiency (ISD) indications.

Methods: One hundred twenty-five patients with SUI were prospectively evaluated following a re-adjustable sling in a single tertiary academic Center. Patients were classified by Q-tip, urodynamic and clinical criteria into ISD (70) and recurrent SUI (55).

[Assessment of the health-related quality of life impact in female with mixed urinary incontinence].

Background: Health-related quality of life (HRQoL) assessment on female with urinary incontinence (UI) may be a useful indicator in the management of early treatment depending on the sort of UI which is dominant: Stress UI or Urge UI. The objective of the present study was to evaluate the HRQoL of female with mixed UI, comparing the impact of symptoms of Urge UI and Stress UI.

Patients And Methods: This is an epidemiologic, cross-sectional and multicenter study.

Solifenacin in the treatment of urgency and other symptoms of overactive bladder: results from a randomized, double-blind, placebo-controlled, rising-dose trial.

Objectives: To examine the effects of the antimuscarinic agent solifenacin on urinary urgency, using a range of novel and established outcome measures, as urgency is the principal symptom of the overactive bladder syndrome (OAB).

Patients And Methods: The study (SUNRISE, solifenacin in the treatment of urgency symptoms of OAB in a rising dose, randomized, placebo-controlled, double-blind, efficacy trial) was a randomized, double-blind, 16-week, placebo-controlled, multicentre study of solifenacin 5/10 mg in 863 patients with symptoms of OAB for > or = 3 months. The primary efficacy variable was the change from baseline to endpoint in the number of episodes of severe urgency with or without urgency incontinence per 24 h, as measured using the Patient Perception of Intensity of Urgency Scale, grade 3 + 4.

Cizolirtine citrate, an effective treatment for symptomatic patients with urinary incontinence secondary to overactive bladder: a pilot dose-finding study.

Background: A dose-finding study was performed as the first step in the clinical development of the new drug, cizolirtine citrate.

Objective: To assess the efficacy and safety of cizolirtine citrate in overactive bladder with urinary incontinence.

Design, Setting, And Participants: Seventy-nine outpatients with clinical overactive bladder and/or urodynamic diagnosis of detrusor overactivity were randomized in a multicentre, 12-wk, double-blind, pilot trial.

Detrusor quantitative morphometry in obstructed males and controls.

Purpose: We studied the usefulness of computer assisted morphometry for measuring detrusor muscle cell diameter and the connective tissue-to-smooth muscle ratio in patients with bladder outlet obstruction, acute urinary retention and a nonobstructed control group.

Materials And Methods: A prospective study was done in patients with bladder outlet obstruction undergoing transurethral prostate resection. Patients were divided into 33 with obstruction and 14 in acute urinary retention.

[The presence of a prolene mesh in the vagina].

Objective: To describe the clinical case of a patient presenting complications after the implantation of a Prolene mesh as reinforcement for the correction of a recurrent cystocele.

Methods/results: Seventy-five-years-old female patient with history of previous cystocele repair with Prolene mesh presenting urinary incontinence and vaginal erosion of the mesh.

Conclusions: The use of mesh for the repair of cystoceles has the advantage of providing greater support to the colporrhaphy and avoiding recurrences.

Bladder blood flow and de-obstructive open prostatectomy: correlation with clinical and urodynamic parameters.

Purpose: To assess the relation between tissue blood flow changes during surgery with clinical and urodynamic parameters in obstructed patients.

Material And Methods: A prospective study was conducted in 18 symptomatic patients with bladder outlet obstruction undergoing retropubic prostatectomy. A symptom assessment and a preoperative urodynamic study were performed.

Is bladder cycling useful in the urodynamic evaluation previous to renal transplantation?

Objectives: To evaluate the usefulness of bladder cycling (BC) in differentiating between urodynamic abnormalities due to reversible bladder dysfunction and those due to preexisting lower urinary tract (LUT) abnormalities, and to determine if BC increases the diagnostic yield of urodynamic investigations (UIs) in these patients.

Methods: Eleven patients with oligoanuria (<300 ml/day) were evaluated with complete UIs. All cases showed low compliance (mean 6 ml/cm H2O) and low cystometric capacity (mean 146 ml) and were placed in a BC program.

Solifenacin appears effective and well tolerated in patients with symptomatic idiopathic detrusor overactivity in a placebo- and tolterodine-controlled phase 2 dose-finding study.

Objectives: To evaluate the dose-response relationship and safety/tolerability of solifenacin succinate (YM905) in the treatment of overactive bladder (OAB), and to compare its efficacy and safety/tolerability with tolterodine 2 mg twice daily.

Patients And Methods: This multicentre study included a 2-week single-blind placebo run-in, a 4-week double-blind placebo-controlled active treatment phase, and a 2-week follow-up. Men and women with an OAB and urodynamic evidence of detrusor overactivity were randomized to placebo or solifenacin 2.

Urodynamic evaluation and management prior to renal transplantation.

Objectives: To evaluate the indications for urodynamics studies (UDS) previous to renal transplantation (RT) and the results of bladder cycling (BC), performed in selected cases.

Methods: Among 475 RT, 33 patients (6.9%) required UDS according our protocol.

Clear cell adenocarcinoma in a female urethral diverticulum.

The incidence of a neoplasm within the female urethral diverticulum is rare. Clear cell adenocarcinoma, which is the most common neoplasm, arises from the metaplasia of surface transitional epithelium and the paraurethral ducts. These tumors are usually diagnosed at a late stage, which worsens their prognosis.

The reliability of cysto-urethrographic signs in the diagnosis of detrusor instability in children.

Objective: To assess whether the signs associated with detrusor instability (DI), as assessed by video-urodynamic studies, can be evaluated by conventional voiding cysto-urethrography (VCUG).

Patients And Methods: Fifty-nine children who underwent cystometry and VCUG were reviewed and divided into two groups; group 1 comprised 51 neurologically normal children who had DI (47 girls and four boys, mean age 7.9 years, range 4-14), with no malformations or previous surgery.

Polytetrafluoroethylene sling for failure in female stress incontinence surgery.

Surgery for stress urinary incontinence (SUI) in women with previous interventions is often difficult and yields poor results. A total of 33 women with recurrent SUI underwent placement of a polytetrafluoroethylene (PTFE) sling after a mean of 1.5 (range, 1-3) unsuccessful operations.

[The urologist's language: a survey on symptoms].

The definition of urologic symptoms varies depending on the source. Some symptoms are particularly vague and their clinical usefulness is doubtful. A survey was sent to 500 spanish urologists, asking about terminology and normality limits.

[Endoscopic injection of Teflon in urinary incontinence in women].

Over a one year period (September 1981 - September 1982) the authors carried out the subcervical injection of Teflon in 26 cases, 20 of which were suitable for inclusion in the present study. All the patients had true stress incontinence. Nine had undergone previous surgery, 8 had sphincter incompetence with an intact perineum and 3 were obese and/or in poor general condition.