Publications by authors named "Aram Halimi"
Background: Ubiquitin-specific peptidases (USPs), also known as deubiquitinating enzymes (DUBs), play a crucial role in maintaining cellular homeostasis by selectively removing ubiquitin molecules from targeted proteins. This process affects protein stability, subcellular localization, and activity, thereby influencing processes such as DNA repair, cell cycle regulation, and apoptosis. Abnormal USP activities have been linked to various diseases, including cancer.
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- - The study aimed to evaluate the impact of the COVID-19 lockdown on glycaemic control in adolescents (ages 10-19) with type 1 diabetes, focusing on average glucose levels and HbA1c.
- - A systematic review included 14 studies that compared glucose levels before, during, and after the lockdown, finding a decrease in average glucose during the lockdown but a rise afterward.
- - While a descriptive analysis suggested that lockdown reduced average glucose levels, the overall results from the meta-analysis were not statistically significant, indicating uncertainties about the lockdown's true effect.
Objective: This study aims to evaluate the epidemiology of asthma among children and adolescents in the Eastern Mediterranean Region.
Methods: Exhaustive searches were conducted across databases, including PubMed, Scopus, Web of Knowledge Core Collection, Embase, and Google Scholar. The selection criteria included studies reporting asthma prevalence in individuals aged 0 to 19 years, using validated questionnaires.
Introduction: The Knowledge, Attitudes, and Practices (KAP) model is a foundational tool in public health research. KAP surveys play a vital role in this process by gauging a population's current level of knowledge about a specific health issue. Rigorous evaluation is essential for ensuring the validity and reliability of KAP studies.
View Article and Find Full Text PDFBackground: Leukemia, a type of blood cell cancer, is categorized by the type of white blood cells affected (lymphocytes or myeloid cells) and disease progression (acute or chronic). In 2020, it ranked 15th among the most diagnosed cancers and 11th in cancer-related deaths globally, with 474,519 new cases and 311,594 deaths (GLOBOCAN2020). Research into leukemia's development mechanisms may lead to new treatments.
View Article and Find Full Text PDFBackground: The aim of this study was to conduct a systematic review and meta-analysis to estimate the prevalence of needle-stick injury among Iranian nurses.
Methods: We conducted a systematic review and meta-analysis to estimate the prevalence of needle-stick injury among Iranian nurses. A comprehensive search of Web of Science, PubMed, Scopus, Scientific Information Database, and MagIran was performed, yielding 29 observational articles comprising 8842 nurses.
Background: Colorectal cancer (CRC) is the third most frequent and the second most fatal cancer. The search for more effective drugs to treat this disease is ongoing. A better understanding of the mechanisms of CRC development and progression may reveal new therapeutic strategies.
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- - ADHD is underdiagnosed in adults globally, with specific challenges in the Arab region, including stigma and inadequate healthcare resources, particularly in the UAE.
- - A study conducted among first-year university students in the UAE found that approximately 34.7% exhibited symptoms of probable ADHD, with those showing symptoms having lower academic performance.
- - The results suggest a higher prevalence of ADHD symptoms among females than males, highlighting the need for improved screening methods and mental health services in the region.
The impact of cultural healthcare practices on Children's health in the United Arab Emirates: a qualitative study of traditional remedies and implications.
Front Public Health
October 2023
Aim: This qualitative study investigates the impact of cultural practices on children's health in the United Arab Emirates (UAE) by examining the use of traditional remedies and home treatments by mothers.
Methods: Twenty-five participants, all mothers who had employed traditional treatments or home remedies for their children during periods of illness, were included in the study. The participants represented a diverse range of educational backgrounds, from school diploma holders to university degree graduates, with ages spanning from 20 to 50 years.
REPCAN: Guideline for REporting Population-based CANcer Registry Data.
Asian Pac J Cancer Prev
September 2023
Background: The objective of this study was to develop a guideline on how to report result of a population-based cancer registry. Methods: The guideline's development involved a core working committee and a scientific committee comprising experts from diverse domains. The process comprised three steps: 1) a comprehensive review of existing tools and guidelines and the development of the initial draft of the guideline based on a review of literature, 2) refinement items through several rounds of focus group discussion among the core group, and development initial draft, and 3) Evaluation of the initial draft by scientific committee members.
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