Publications by authors named "Araji Ghada"

Vitamin B12 deficiency is a significant concern among patients with end-stage renal disease undergoing dialysis. However, there hasn't been extensive research conducted on this particular patient group. The reported incidence rates vary widely, ranging from 20% to 90%, reflecting the complexity of its diagnosis.

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  • Hemophilia, a bleeding disorder, poses higher risks for adverse outcomes and longer hospital stays for patients undergoing percutaneous coronary intervention (PCI) due to acute coronary syndrome (ACS).
  • A study using data from the Nationwide Inpatient Sample Database revealed that individuals with hemophilia had significantly higher rates of gastrointestinal bleeding, hemorrhagic stroke, and retroperitoneal hemorrhage compared to those without the condition.
  • The findings stress the importance of proper management of coagulation factors and collaboration between cardiologists and hematologists to improve patient outcomes in this vulnerable population.
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There is a paucity of data on the cardiovascular implications of monoclonal gammopathy of undetermined significance, especially among hospitalized patients. Our study aimed to investigate the association between MGUS and cardiovascular outcomes in a hospital setting using the National Inpatient Sample database. MGUS patients were sampled using ICD-10 codes.

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Introduction: Renal squamous cell carcinoma (SCC) is a neoplasm with an extremely rare occurrence compared to other renal malignancies. The classic presentation includes a palpable mass and flank pain; however, the presentation is seldom non-specific. Our study describes the significance of programmed death ligand-1 (PD-L1) expression in renal cancer and its association with clinical outcomes, alongside available treatment options.

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The advancement of renal replacement therapy has significantly enhanced the survival rates of patients with end-stage renal disease (ESRD) over time. However, this prolonged survival has also been associated with a higher likelihood of cancer diagnoses among these patients including breast cancer. Breast cancer treatment typically involves surgery, radiation, and systemic therapies, with approaches tailored to cancer type, stage, and patient preferences.

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  • Disseminated intravascular coagulation (DIC) is a frequent but serious complication in Acute Myeloid Leukemia (AML), linked to increased cardiovascular issues not previously reported.* -
  • In a study analyzing 37,344 AML patients, those with DIC were younger, predominantly male, and showed significantly higher rates of mortality and acute cardiovascular events like myocardial infarction and pulmonary edema.* -
  • The research stresses the need for vigilant cardiovascular monitoring in AML patients with DIC, pointing to complex biological factors that contribute to these complications and suggesting further research for better management strategies.*
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Prostate cancer ranks as the second most common malignancy in males. Prostate cancer progressing on androgen deprivation therapy (ADT) is castration-resistant prostate cancer (CRPC). Poly-ADP ribose polymerase (PARP) inhibitors (PARPis) have been at the forefront of the treatment of CRPC.

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The discovery of immune checkpoint inhibitors (ICIs) has revolutionized the care of cancer patients. However, the response to ICI therapy exhibits substantial interindividual variability. Efforts have been directed to identify biomarkers that predict the clinical response to ICIs.

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