Publications by authors named "Aradhna Seth"
Background: The development of point-of-care biomarkers of disease has become a major focus of interest in nonalcoholic fatty liver disease (NAFLD). The NAFLD fibrosis score (NFS), BARD, FIB-4, and aspartate aminotransferase-to-platelet ratio index (APRI) are commonly used for advanced NAFLD fibrosis prediction. However, the performance of these scores among in a predominantly Hispanic patient population, a population with the highest prevalence of NAFLD, has not been examined.
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- Paediatric non-alcoholic fatty liver disease (NAFLD) is common in children with obesity, and the study aimed to explore the link between obesity severity and NAFLD severity.
- A retrospective cohort study used data from Cincinnati Children's Medical Center, categorizing patients by BMI and assessing liver disease severity using biochemical, imaging, and histological methods.
- Results indicated that higher obesity severity (especially class III obesity) is associated with more advanced liver disease, highlighting the importance of obesity classification for treatment and monitoring.
Community Socioeconomic Deprivation and Nonalcoholic Fatty Liver Disease Severity.
J Pediatr Gastroenterol Nutr
March 2020
Background And Objectives: Nonalcoholic fatty liver disease (NAFLD) is linked to obesity. Obesity is associated with lower socioeconomic status (SES). An independent link between pediatric NAFLD and SES has not been elucidated.
View Article and Find Full Text PDFThe leading cause of non-HIV-related mortality is liver disease. Fatty liver disease can be characterized as alcoholic or nonalcoholic in nature. Alcohol use is prevalent among individuals with HIV infection and can lead to medication nonadherence, lower CD4+ cell count, inadequate viral suppression, and disease progression.
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