Evaluation of In Vitro Activity of Ceftazidime-Avibactam and Colistin with VITEK 2 AST-XN21.

Background: Ceftazidime-avibactam and colistin are antibiotics of new and regaining importance used for the treatment of infections caused by multidrug-resistant organisms. The broth microdilution (BMD) test recommended for detecting colistin sensitivity is labor-intensive and difficult to perform under routine conditions. There is a need for alternative methods that produce fast and reliable results in routine laboratory studies.

Comparison of intra-assay and inter-assay reproducibility and positive detection times of two different (BacT/Alert 3D and Autobio BC) commercial blood culture systems.

Purpose: In our study, we aimed to compare the performance of the BacT/Alert 3D (bioMerieux, France) system, which is currently used in our laboratory, and the Autobio BC (Autobio, China) system, which was newly introduced in our country, using standard and clinical isolates.

Methods: Bacterial suspension was prepared by two technicians on the same day and three consecutive days from five different standard strains with 0.5 McFarland turbidity, then serial dilution to a final concentration was adjusted and was simultaneously inoculated in aerobic blood culture bottles.

Carbapenem-resistant Klebsiella pneumoniae outbreak with monoclonal spread: Evaluation of resistance genes and ceftazidime-avibactam susceptibility.

Purpose: The aim of this study was to investigate ceftazidime-avibactam (CAZ-AVI) susceptibility, carbapenemase genes, and clonal relationship in carbapenem-resistant Klebsiella pneumoniae (CrKp) isolates.

Methods: A total of 28 non-repetitive CrKp isolates with positive carbapenemase production determined by the modified carbapenem inactivation method (mCIM), were included in the study. Identification of the isolates was performed with MALDI-TOF MS (VITEK-MS, bioMerieux, France).

[A Case of Mycobacterium abscessus Identified by Suspicious Gram Staining in the Blood Culture of a Patient with Chronic Renal Failure].

Mycobacterium abscessus (M.abscessus), which is from the group of non-tuberculosis mycobacteria and is widely found in the natural environment, has been reported with increasing frequency as the causative agent of various infections; especially in the lower respiratory tract and in immuncompromised people. In this report, a case of M.

[Evaluation of In vitro Efficacy of Meropenem/Colistin and Meropenem/Fosfomycin Combinations on Multidrug Resistant Gram-Negative Bacilli].

The rate of extensively drug-resistant and pan-resistant gram-negative rods isolated as infectious agents is increasing around the world and in Türkiye. One of the important options in the treatment of these infections is the combined use of antibiotics. Therefore, the aim of this study was to investigate the in vitro effect of meropenem/colistin and meropenem/fosfomycin combinations on carbapenem-resistant gram-negative bacilli isolated as infectious agents.

Investigation of in vitro efficacy of meropenem/polymyxin B and meropenem/fosfomycin combinations against carbapenem resistant Klebsiella pneumoniae strains.

The incidence of infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) is increasing worldwide, and very limited number of effective antibiotics are available for therapy. In our study, the in vitro efficacy of meropenem/polymyxin B and meropenem/fosfomycin combinations against CRKP strains was investigated. The efficiency of meropenem/polymyxin B and meropenem/fosfomycin combinations was tested by checkerboard microdilution and checkerboard agar dilution methods, respectively, against 21 CRKP strains containing major carbapenem resistant genes (7 blaKPC, 7 blaOXA-48 gene, and 7 blaOXA-48+ blaNDM), and seven additional CRKP strains without carbapenemase genes.

Evaluation of Broth Disk Elution Method to Determine Colistin Resistance in Klebsiella pneumoniae and Escherichia coli Strains.

Background: The reference broth microdilution (rBMD) method for the determination of colistin resistance is very laborious and time consuming, and many manual errors can occur. There are also limitations in detection of colistin heteroresistance. Therefore, alternative methods with satisfactory performance are required for routine laboratory work.

Comparison of performance of LIAISON SARS-CoV-2 antigen assay with RT-PCR during the Omicron wave.

Due to the newly emerging Omicron variant, there is a need to re-evaluate the performance of automated antigen tests. Our study aim was to evaluate the performance of the automated Liaison SARS-CoV-2 antigen assay against reverse transcriptase polymerase chain reaction (RT-PCR) in samples with Omicron variant.A prospective study was performed on 373 combined oro-nasopharyngeal samples (NPS) randomly collected from symptomatic patients.

Performance of the Rapidec®Carba NP assay for the detection of different carbapenemases in Klebsiella pneumoniae and Escherichia coli strains.

Purpose: The spread of infections caused by Enterobacterales strains resistant to carbapenems is a global public health problem, and early detection of carbapenemases is very important to prevent their spread. The rapid detection of carbapenemase production with the new commercial assay Rapidec® Carba NP test is based on the biochemical detection of imipenem hydrolysis. Our study aims to evaluate the performance of the Rapidec® Carba NP test in OXA-48 positive isolates highly prevalent in our country and also in isolates with more than one carbapenemase gene that have an increased prevalence and to examine whether it can be used for confirmation of carbapenemase positivity in the routine laboratory.

Rapid detection of fosfomycin resistance in Escherichia coli and Klebsiella spp. strains isolated from urinary tract infections.

This study evaluates whether the rapid fosfomycin resistance (fosfomycin NP) method can be used for detecting fosfomycin resistance in routine laboratory work. Results from the disk diffusion and rapid fosfomycin NP methods were compared with the reference agar dilution method for Escherichia coli and Klebsiella spp. strains isolated from urinary tract infections.

Effectiveness of medical coating materials in decreasing friction between orthodontic brackets and archwires.

Objective: The aim of this study was to evaluate the changes in friction between orthodontic brackets and archwires coated with aluminum oxide (AlO), titanium nitride (TiN), or chromium nitride (CrN). In addition, the resistance of the coatings to intraoral conditions was evaluated.

Methods: Stainless steel canine brackets, 0.

Bartonella henselae IgM seropositivity in both adult and pediatric patients with diverse clinical conditions in Turkey.

Bartonella henselae is the causative agent of cat scratch disease (CSD). In this study, we aimed to investigate the clinical data of patients with suspicion of CSD and delineate current epidemiological features.A total of 785 patients with suspected CSD were included in the study.

Dose-related effects of extracorporeal shock waves on orthodontic tooth movement in rabbits.

The purpose of this animal study is to investigate the quantitative effects of extracorporeal shock waves applied at two different impulses and with two different applicators on orthodontic tooth movement. Thirty-five New Zealand rabbits were randomly divided into five groups (n = 7): the four experimental extracorporeal shock wave groups-focused/500 impulses, focused/1000 impulses, unfocused/500 impulses, and unfocused/1000 impulses-and the control group. Orthodontic tooth movement was achieved by application of reciprocal force between two maxillary incisors.

Buccolingual Inclination Effects of Self-Ligating and Conventional Premolar Brackets: A Cone Beam Computed Tomography Study.

Objective: This study aimed to compare the effects of passive self-ligating (PSL) and conventional ligating (CL) of brackets on the buccolingual inclination (BLINC) of the maxillary premolars.

Methods: This in vitro study included a PSL bracket group and a CL bracket group. Acrylic teeth on typodonts were aligned using 0.

Are age and radiographic features effective on orthodontic alignment of palatally impacted maxillary canines? a retrospective study.

Purpose: The purpose of the study was to evaluate the effects of age and radiographic parameters on success of orthodontic alignment of impacted maxillary canines.

Materials And Methods: The retrospective records of 50 patients (mean age 20.44 years) who had impacted maxillary canines in palatal position were included.

In-vivo effects of flapless osteopuncture-facilitated tooth movement in the maxilla and the mandible.

Background: This study aimed to investigate the effects of a minimally invasive, flapless procedure to enhance tooth movement in both jaws and to determine whether this triggers the acceleration when repeated monthly.

Material And Methods: The sample consisted of thirty-two individuals whose orthodontic treatment required canine retraction. They were divided into an experimental group and control group.

Comparison of arch width changes following orthodontic treatment with and without extraction using three-dimensional models.

Objective: To compare the arch width changes in patients treated fixed orthodontic mechanics without extraction (Group 1), with upper and lower first premolar extractions (Group 2), and with upper first premolar extraction only (Group 3).

Materials And Methods: The study was conducted with pre- and post-treatment digital models from 240 patients. Anterior, middle, and posterior distances were measured on pre- and post-treatment models.

The Radiological and Stereological Analysis of the Effect of Low-Level Laser Therapy on the Mandibular Midline Distraction Osteogenesis.

Objective: The aim of this study was to evaluate the effect of low level laser therapy (LLLT) on bone mineral density by using high-resolution computerized tomography (HR-CT) and stereology in patients subjected to mandibular midline distraction.

Methods: Nine patients between the ages of 13 and 16 years with mandibular transverse deficiency (>5 mm) were evaluated. Mandibular midline distraction osteogenesis was performed for all the patients.

Is children's Body Mass Index associated with their parents' personality? A prospective controlled trial.

Background: The aim of this study was to elucidate the effect of the personal characteristics and psychological status of parents on their children's Body Mass Index (BMI) by using validated questionnaires.

Methods: Obese and healthy control group was assessed with The Parental Attitude Research Instrument (PARI) for the evaluation of parental attitudes towards their children. Additionally, Depression Anxiety and Stress Scale (DASS) were used to assess the relationships between parental depression, anxiety, stress and childhood obesity.

Comparison of the frictional characteristics of aesthetic orthodontic brackets measured using a modified in vitro technique.

Objective: The coefficients of friction (COFs) of aesthetic ceramic and stainless steel brackets used in conjunction with stainless steel archwires were investigated using a modified linear tribometer and special computer software, and the effects of the bracket slot size (0.018 inches [in] or 0.022 in) and materials (ceramic or metal) on the COF were determined.

Shear bond strength of orthodontic attachments bonded to impacted teeth under in vivo and in vitro conditions.

Objectives: To evaluate and compare the shear bond strength (SBS) of stainless steel and gold-plated attachments to impacted lower third molars in vivo and in vitro with a light-cured orthodontic resin.

Setting And Sample Population: Sixteen patients with bilaterally full soft tissue impaction of lower third molars were recruited on a voluntary basis from an oral and maxillofacial surgery department.

Materials And Methods: A split-arch technique was used.

Multidisciplinary management of a fused tooth: a case report.

Objective. Fusion is a dental anomaly that arises through the union of two adjacent teeth. The case report presents multidisciplinary management of a fused maxillary anterior tooth.

The clinical and laboratory effects of bracket type during canine distalization with sliding mechanics.

Objective: To compare the extent of canine movement with sliding mechanics between a self-ligating (SC) bracket and a modified twin design (MT) bracket. To test the in vitro coefficient of friction (COFs) of these two metal brackets on 0.019- × 0.

An evaluation of factors associated with persistent primary teeth.

The aim of the present study was to investigate the reasons for the persistence of primary teeth and also use panoramic radiography to determine the characteristics of persistence teeth. Four-hundred and twenty-six panoramic radiographies, which diagnosed one or more retained primary teeth, were selected from 100,577 panoramic radiographic image files from nine clinics and six different cities in Turkey. The selected radiographies were evaluated to determine the reasons for the persistence of primary teeth; furthermore, this study analyzed the characteristics of the retained primary teeth including tooth type, number, location, and root resorption, and whether, or not, the primary teeth showed evidence of pathological conditions, such as periodontal problems, caries, ankylosis, infra-occlusions, or tipping of the adjacent permanent teeth.

Retrospective analysis of impacted first and second permanent molars in the Turkish population: a multicenter study.

Objectives: The purpose of the present study was to retrospectively analyze 170 case series of patients with 200 impacted first and second permanent molars.

Study Design: Records of 104.408 patients were retrospectively screened in this multicenter study.