Publications by authors named "Aqsa Anwar"
RET proto-oncogene encodes receptor tyrosine kinase. Selpercatinib and pralsetinib are the only RET-specific tyrosine kinase inhibitors approved by FDA in RET-altered tumors. We searched PubMed, Embase, Cochrane, WOS, and Clinicaltrials.
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- - Breast cancer is the second leading cause of cancer-related deaths; antibody-drug conjugates (ADCs) target specific tumor proteins, offering potent treatment with less toxicity compared to traditional chemotherapy.
- - A meta-analysis of 14 clinical trials (N = 5,960) found that ADCs significantly improved progression-free survival (PFS) and overall survival (OS) in patients with HER-2 positive and triple-negative breast cancer compared to chemotherapy.
- - The study highlighted that among ADCs, trastuzumab-deruxtecan (T-der) showed superior effectiveness over trastuzumab-emtansine (T-DM1), with common serious side effects including anemia and fatigue observed in a small percentage of
Novel coronavirus disease (COVID-19) pandemic: A recent mini review.
Comput Struct Biotechnol J
December 2020
The COVID-19, caused by a novel coronavirus, was declared as a global pandemic by WHO more than five months ago, and we are still experiencing a state of global emergency. More than 74.30 million confirmed cases of the COVID-19 have been reported globally so far, with an average fatality rate of almost 3.
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