Synopsis of recent research by authors named "Apurwa Sharma"
- Apurwa Sharma's recent research primarily focuses on understanding tauopathies and their associated protein aggregation mechanisms, particularly the role of tau prion strains in neurodegenerative diseases like Alzheimer's.
- The development of a gene therapy targeting autosomal dominant Alzheimer's disease has been a significant aspect of their work, aiming to address the early-onset form of the disease caused by mutations in key genes such as presenilin 1 and amyloid precursor protein.
- Sharma has also investigated the structural characteristics of tau monomers and their influence on the aggregation process, providing insights into potential therapeutic targets for preventing toxic oligomer formation associated with tau and amyloid-beta aggregates in Alzheimer's pathology.
