Publications by authors named "Appesh Mohandas"
Article Synopsis
- The study aimed to analyze how negative social and behavioral factors (SBDH) affect health care usage among heart failure patients at a safety-net community hospital.
- Out of 4,594 heart failure patients analyzed, 21% faced at least one adverse social or behavioral determinant, with a notable demographic skew towards younger Black males on Medicaid.
- Those with adverse SBDH experienced higher rates of hospitalizations and emergency department visits, indicating that these factors are linked to increased healthcare usage and serve as independent predictors for hospital readmissions.
Plasma metabolomics profiling is an emerging methodology to identify metabolic pathways underlying cardiovascular health (CVH). The objective of this study was to define metabolomic profiles underlying CVH in a cohort of Black adults, a population that is understudied but suffers from disparate levels of CVD risk factors. The Morehouse-Emory Cardiovascular (MECA) Center for Health Equity study cohort consisted of 375 Black adults (age 53 ± 10, 39% male) without known CVD.
View Article and Find Full Text PDFPrior work suggests blood pressure in African Americans is more sensitive to the effects of aldosterone than in Caucasians. This mechanism may relate to a negative response of the vascular endothelium to aldosterone, including reduced glucose-6-phosphate dehydrogenase (G6PD) activity. Thirty-three African Americans (11 hypertensives, 22 controls) without evidence of diabetes or metabolic syndrome completed the protocol.
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