Publications by authors named "Appel J"

Background: Newer studies raise concern that adjuvant anthracycline treatment for breast cancer (BC) causes long-term heart damage. We aimed to examine whether heart failure or impairment could be demonstrated several years after low-dose epirubicin-based adjuvant treatment.

Material And Methods: The study-population was a historical cohort comprising 980 women who were randomized to receive one of two adjuvant regimens for treatment for BC: 7-9 cycles of cyclophosphamide-epirubicin-5-fluorouracil [CEF (600 + 60 + 600 mg/m(2))] or cyclophosphamide-methotrexate-5- fluorouracil [CMF (600 + 40 + 600 mg/m(2))].

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We report on a search for the standard model Higgs boson decaying into pairs of τ leptons in pp collisions produced by the Tevatron at sqrt[s]=1.96  TeV. The analyzed data sample was recorded by the CDFII detector and corresponds to an integrated luminosity of 6.

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We have measured the W-boson mass M(W) using data corresponding to 2.2  fb(-1) of integrated luminosity collected in pp collisions at sqrt[s] = 1.96  TeV with the CDF II detector at the Fermilab Tevatron collider.

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The angular distributions of muons from Υ(1S,2S,3S) → μ+ μ- decays are measured using data from pp collisions at sqrt[s] = 1.96  TeV corresponding to an integrated luminosity of 6.7  fb(-1) and collected with the CDF II detector at the Fermilab Tevatron.

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Anthracycline treatments are hampered by dose-related cardiotoxicity, frequently leading to heart failure (HF) with a very poor prognosis. The authors report a case of a 19-year-old man developing HF after anthracycline treatment for Ewing sarcoma. Despite medical treatment, his condition deteriorated to terminal HF, leading to implantation of a mechanical left ventricular assist device (LVAD).

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We report an indirect search for nonstandard model physics using the flavor-changing neutral current decays B→K(*)μ(+)μ(-). We reconstruct the decays and measure their angular distributions, as a function of q(2)=M(μμ)(2)c(2), where M(μμ) is the dimuon mass, in pp¯ collisions at √s=1.96 TeV using a data sample corresponding to an integrated luminosity of 6.

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We have observed exclusive γγ production in proton-antiproton collisions at √s=1.96 TeV, using data from 1.11±0.

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In this Letter, we present a precise measurement of the total ZZ production cross section in pp collisions at sqrt[s]=1.96  TeV, using data collected with the CDF II detector corresponding to an integrated luminosity of approximately 6  fb(-1). The result is obtained by combining separate measurements in the four-charged (ℓℓℓ' ℓ') and two-charged-lepton and two-neutral-lepton (ℓℓνν) decay modes of the Z boson pair.

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Preimplantation genetic diagnosis offers the possibility of screening and terminating embryos with severe and life-threatening disabilities. This article argues that under certain conditions, the use of this technology is not merely desirable as a means to reduce human suffering but also an ethically required duty of a parent to a potential child.

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A search for a narrow Higgs boson resonance in the diphoton mass spectrum is presented based on data corresponding to 7.0  fb{-1} of integrated luminosity from pp collisions at sqrt[s]=1.96  TeV collected by the CDF experiment.

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We present a measurement of the B(s)(0) lifetime in fully and partially reconstructed B(s)(0)→D(s)(-)(ϕπ(-))X decays in 1.3  fb(-1) collected in pp ¯ collisions at √s=1.96 TeV by the CDF II detector at the Fermilab Tevatron.

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We present the first measurement of polarization and CP-violating asymmetries in a B(s)(0) decay into two light vector mesons, B(s)(0)→φφ, and an improved determination of its branching ratio using 295 decays reconstructed in a data sample corresponding to 2.9 fb(-1) of integrated luminosity collected by the CDF experiment at the Fermilab Tevatron collider. The fraction of longitudinal polarization is determined to be f(L)=0.

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We present the results of a search for pair production of a heavy toplike (t') quark decaying to Wq final states using data corresponding to an integrated luminosity of 5.6 fb(-1) collected by the CDF II detector in pp collisions at √s=1.96 TeV.

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We present a measurement of the top-quark mass using a sample of t ̄t events in 5.7 fb(-1) of integrated luminosity from p ̄p collisions at the Fermilab Tevatron with √s=1.96 TeV and collected by the CDF II Detector.

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We report the first observation of the baryonic flavor-changing neutral current decay Λ(b)(0)→Λμ(+)μ(-) with 24 signal events and a statistical significance of 5.8 Gaussian standard deviations. This measurement uses a pp collisions data sample corresponding to 6.

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We present a search for a new particle T' decaying to a top quark via T' → t + X, where X goes undetected. We use a data sample corresponding to 5.7 fb(-1) of integrated luminosity of p p collisions with sqrt[s] = 1.

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A search has been performed for B(s)(0) → μ+ μ- and B(0) → μ+ μ- decays using 7 fb(-1) of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron collider. The observed number of B(0) candidates is consistent with background-only expectations and yields an upper limit on the branching fraction of B(B(0) → μ+ μ-) < 6.0 × 10(-9) at 95% confidence level.

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We present a search for new physics in events with two high pT leptons of the same electric charge, using data with an integrated luminosity of 6.1 fb(-1). The observed data are consistent with standard model predictions.

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This Letter reports a measurement of the cross section of prompt isolated photon pair production in pp collisions at a total energy square root(s)=1.96  TeV using data of 5.36  fb(-1) integrated luminosity collected with the CDF II detector at the Fermilab Tevatron.

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The observation of the bottom, strange baryon Ξ(b)(0) through the decay chain Ξ(b)(0)→Ξ(c)(+)π-, where ΞΞ(c)(+)→Ξ- π+ π+, Ξ-→Λπ-, and Λ→pπ-, is reported by using data corresponding to an integrated luminosity of 4.2  fb(-1) from pp collisions at square root(s)=1.96  TeV recorded with the Collider Detector at Fermilab.

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Pituitary adenomas rarely originate outside the sella turcica. Ectopic locations include the suprasellar region, sphenoid sinus, cavernous sinus and clivus. We describe a 50-year-old female who presented with clinical signs and biochemical evidence of acromegaly.

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The threat of bioterrorism with smallpox and the broad use of vaccinia vectors for other vaccines have led to the resurgence in the study of vaccinia immunological memory. The importance of the role of CD4+ T cells in the control of vaccinia infection is well known. However, more CD8+ than CD4+ T cell epitopes recognized by human subjects immunized with vaccinia virus have been reported.

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