Optical Coherence Tomography Angiography Biomarkers in Thai Patients With Diabetic Nephropathy: A Diabetic Eye and Kidney Diseases (DEK-D) Study.

Purpose: To identify optical coherence tomography angiography (OCTA) biomarkers to predict the diabetic nephropathy (DN) and their associations with 24-hour urine albumin levels in diabetic patients.

Methods: This cross-sectional, observational study examined 186 eyes from 93 individuals subdivided into three groups according to 24-hour urine albumin levels: no DN, early DN, and late DN. Vessel density (VD), fractal dimension, foveal avascular zone area, intercapillary area, central retinal thickness, and subfoveal choroidal thickness were measured from OCTA images to determine their association with the DN stages.

The sterility, stability and efficacy of repackaged ziv-aflibercept for intravitreal administration.

To evaluate the sterility, stability, and efficacy of repackaged ziv-aflibercept in 1-mL plastic tuberculin syringes for intravitreal injection after storage for up to 90 days at controlled (4 °C) and ambient (25.8 °C) temperature. A total of 168 tuberculin-type 1-mL syringes were prepared containing ziv-aflibercept (100 mg/4 mL).

Outcomes of Pre-Early Treatment for Retinopathy of Prematurity (Pre-ETROP).

Introduction: The earlier treat stage 3 ROP is more likely to achieve better outcomes.

Primary Purpose: To study the unfavorable outcomes and regression after pre-early treatment for ROP.

Secondary Purpose: To evaluate the progression and recurrence of ROP requiring retreatment after pre-early treatment for ROP.