In vivo imaging of ferroptosis through nanodynamic changes in lipid membranes.

Ferroptosis emerged as a cell death modality for drug resistant cancer cells, but there are currently no available biomarkers for imaging ferroptosis based therapies. To address this gab, we evaluated the nanodynamic changes in lipid membranes occurring during cell death to explore potential targeting opportunities to image cell death. We nano-sized gaps at late stages of ferroptosis can serve as entry points for dyes that can bind to cellular structures.

Diversity ideologies in organizations.

This review examines diversity ideologies as influential tools for managing intergroup relations in organizations. Drawing from over two decades of scholarship, we consider our evolving understanding of what diversity ideologies are, how they manifest, and what consequences they have. Diversity ideologies are multi-level constructs that can be espoused or enacted.

Transparency about lagging diversity numbers signals genuine progress.

Numerous organizations pledge to increase diversity, yet few publicly disclose how diverse they are. We suggest this reluctance to be transparent stems from an intuitive (albeit often misplaced) psychological calculation: that revealing struggles to increase diversity will undermine one's credibility and reputation. We evaluate the effects of transparency about lagging diversity numbers across four preregistered studies ( = 4,483), using real EEO-1 diversity disclosures from S&P 100 companies (Study 1) and information about the representation of racial/ethnic minorities in participants' own organizations (Studies 2-4).

How age and race affect the frequency, timing, and content of conversations about race with children.

Anti-racist efforts require talking with children about race. The present work tested the predictors of U.S.

The Line of Ideal Isothermal Compressibility.

We have considered the line along which the values of the isothermal compressibility of a system are the same as they would be for an ideal gas. It was called the κ line. Various substances and models have been studied with the use of the multi-parameter equations of states, implemented in REFPROP (Lemmon, E.

Merging data curation and machine learning to improve nanomedicines.

Nanomedicine design is often a trial-and-error process, and the optimization of formulations and in vivo properties requires tremendous benchwork. To expedite the nanomedicine research progress, data science is steadily gaining importance in the field of nanomedicine. Recently, efforts have explored the potential to predict nanomaterials synthesis and biological behaviors via advanced data analytics.

Believing that prejudice can change increases children's interest in interracial interactions.

Children begin interacting less across racial lines around middle childhood, but it remains unclear why. We examine the novel possibility that, at that time, children's prejudice theories-their understanding of prejudice as a fixed or malleable attribute-begin to influence their desire for interracial affiliation. We devise immersive behavioral experiences to evaluate when and how prejudice theories affect interracial affiliation.

A perception-based nanosensor platform to detect cancer biomarkers.

Conventional molecular recognition elements, such as antibodies, present issues for developing biomolecular assays for use in certain technologies, such as implantable devices. Additionally, antibody development and use, especially for highly multiplexed applications, can be slow and costly. We developed a perception-based platform based on an optical nanosensor array that leverages machine learning algorithms to detect multiple protein biomarkers in biofluids.

Ice Growth Acceleration by Antifreeze Proteins Leads to Higher Thermal Hysteresis Activity.

Since some antifreeze proteins and glycoproteins (AF(G)Ps) cannot directly bind to all ice crystal planes, they change ice crystal morphology by minimizing the area of the crystal planes to which they cannot bind until crystal growth is halted. Previous studies found that growth along the -axis (perpendicular to the basal plane, the crystal plane to which these AF(G)Ps cannot bind) is accelerated by some AF(G)Ps, while growth of other planes is inhibited. The effects of this growth acceleration on crystal morphology and on the thermal hysteresis activity are unknown to date.

Adults delay conversations about race because they underestimate children's processing of race.

To help children navigate their social environments, adults must understand what children know about race, and when they acquire this knowledge. Across three preregistered studies, we tested United States adults' knowledge of when children first use race to categorize and ascribe traits to others. Participants wildly-and uniquely-misjudged children's abilities to process race.

The Line of the Unit Compressibility Factor (Zeno-Line) for Crystal States.

We study the behavior of the line of the unit compressibility factor (Zeno-line) in crystalline states. We used the Lennard-Jones system, experimental -- data for a number of substances, and the Debye model. We found that, contrary to the case of the liquid states, the Zeno-line in a crystal is not a straight line at the density-temperature plane.

Similarity Laws for the Lines of Ideal Free Energy and Chemical Potential in Supercritical Fluids.

We have found the curves on the density-temperature plane, along which the values of free energy and chemical potential correspond to ideal gas quantities. At first, we have applied the van der Waals equation to construct them and to derive their equations. Then we have shown that the same lines for real substances (Ar, N, CH, SF, H, HO) and for the model Lennard-Jones system constructed on the basis of the measurements data and calculations are well matched with the derived equations.

Beyond one-size-fits-all: Tailoring diversity approaches to the representation of social groups.

When and why do organizational diversity approaches that highlight the importance of social group differences (vs. equality) help stigmatized groups succeed? We theorize that social group members' numerical representation in an organization, compared with the majority group, influences concerns about their distinctiveness, and consequently, whether diversity approaches are effective. We combine laboratory and field methods to evaluate this theory in a professional setting, in which White women are moderately represented and Black individuals are represented in very small numbers.

The Zeno Line for Al, Cu, and U.

We show that the property of linearity for a line of unit compressibility factor (Zeno line) can be confirmed for metals (Al, Cu, and U) in liquid phase. The embedded atom potentials (EAM) have been used to describe the interaction between the particles. The numerical simulations within Monte Carlo (MC) technique with the EAM potential have resulted in the straight Zeno-line for considered metals and have allowed us to define the Zeno line parameters.

Maximizing the Gains and Minimizing the Pains of Diversity: A Policy Perspective.

Empirical evidence reveals that diversity-heterogeneity in race, culture, gender, etc.-has material benefits for organizations, communities, and nations. However, because diversity can also incite detrimental forms of conflict and resentment, its benefits are not always realized.

When Societal Norms and Social Identity Collide: the Race Talk Dilemma for Racial Minority Children.

Racial minorities face a unique "race talk" dilemma in contemporary American society: their racial background is often integral to their identity and how others perceive them, yet talk of race is taboo. This dilemma highlights the conflict between two fundamental social processes: social identity development and social norm adherence. To examine how, and with what costs, this dilemma is resolved, 9-12-year-old Latino, Asian, Black, and White children (=108) completed a photo identification task in which acknowledging racial difference is beneficial to performance.

The Wide-Range Method to Construct the Entire Coexistence Liquid-Gas Curve and to Determine the Critical Parameters of Metals.

A method to find the liquid-gas critical parameters of metallic elements is offered. It takes into account a nonanalytic behavior in the critical point vicinity and the Clapeyron-Clausius asymptotic behavior at low temperatures. The present approach provides good agreement with experimental data for a wide wealth of non-metallic substances and mercury and alkali metals, where the critical parameters and binodals are known from the measurements.

The Similarity Relations Set on the Basis of Symmetrization of the Liquid-Vapor Phase Diagram.

An approach to symmetrize the liquid-vapor phase coexistence curve is proposed. It is based on the introduction of the lattice-like density x = ρ1/(ρ1 + ρ2), where ρ1 and ρ2 are the densities along the liquid-gas binodal. The global symmetrical phase diagram is created using experimental and simulation data for the real substances and models (noble gases, polyatomic molecules, organic substances and two metals, van der Waals system, Lennard-Jones system).

Ethnic diversity deflates price bubbles.

Markets are central to modern society, so their failures can be devastating. Here, we examine a prominent failure: price bubbles. Bubbles emerge when traders err collectively in pricing, causing misfit between market prices and the true values of assets.

The similarity law for the Joule-Thomson inversion line.

We show that the expression for the Joule-Thomson inversion temperature following from the van der Waals equation and recorded in a form reduced to the Boyle values has a universal character and can be applied to many real substances and model systems.

Feeling more together: group attention intensifies emotion.

The idea that group contexts can intensify emotions is centuries old. Yet, evidence that speaks to how, or if, emotions become more intense in groups remains elusive. Here we examine the novel possibility that group attention--the experience of simultaneous coattention with one's group members--increases emotional intensity relative to attending alone, coattending with strangers, or attending nonsimultaneously with one's group members.

Rethinking the Baseline in Diversity Research: Should We Be Explaining the Effects of Homogeneity?

It is often surprisingly difficult to make definitive scientific statements about the functional value of group diversity. We suggest that one clear pattern in the group diversity literature is the prevailing convention of interpreting outcomes as the effect of diversity alone. Although work in this arena typically compares diverse groups with homogeneous ones, we most often conceive of homogeneous groups as a baseline-a reference point from which we can understand how diversity has changed behavior or what type of response is "normal.

Note: The universal relations for the critical point parameters.

The universal correlation between the reduced critical pressure, density, and temperature for different substances and model systems was found on the basis of analysis of experimental and numerical simulation data. We choose the Zeno line (ZL) parameters as the reducing units (ZL is the line along which the compressibility factor is unity). In these variables the critical and ZL parameters satisfy simple relations, which are valid for a great number of substances.