Publications by authors named "Apetse K"

Background: Dysfunction of small nerve fibers remains a major public health concern. Subjects suspected of having small nerve fiber damage need to undergo reliable tests to confirm the diagnosis. Sudomotor function test is a reliable noninvasive exploration for detecting peripheral neuropathies.

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 Neuromyelitis optica spectrum disorders (NMOSD) would disproportionately affect blacks within mixed populations. However, they are rarely reported in black African. The objective of this work was to report the experience of Togo, a West African country in terms of NMOSD.

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Introduction: In sub-Saharan Africa characterized by limited resources especially in health facilities and a relatively higher frequency of infectious diseases, studies on Guillain-Barré syndrome (GBS) are rare.

Objectives: The objectives of this work are to describe the characteristics of GBS in Togo through a cohort of patients followed in the neurology unit of the Campus University Hospital of Lomé.

Methodology: The study took place from May 2015 to July 2019.

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Résumé Dans la majorité des cas asymptomatiques, les hémangiomes vertébraux peuvent être, dans de rares cas, symptomatiques avec des manifestations cliniques purement neurologiques. S´ils sont fréquemment observés chez un sujet adulte jeune, ils peuvent exceptionnellement être observés chez un sujet âgé. Nous rapportons un cas d´hémangiome vertébral neuro-agressif de révélation tardive traité par une chirurgie décompressive, une sclérothérapie, une cimentoplastie et suivi d´une évolution favorable.

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A 37-year-old patient was admitted for a left progressive left-hand hemiparesis associated with left C4-C5 neuralgia preceded by inflammatory neck pain for 04 months and dysphagia for 02 weeks. Magnetic resonance imaging showed C3-C5 spondylodiscitis lesions with epidural abscess and predominantly left lateralized compression of the spinal cord and retropharyngeal abscess. The patient was operated for incision and drainage of the retropharyngeal abscess through the oral cavity and Koch bacillus was demonstrated from the aspirate by molecular technique GeneXpert.

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Objective: We report two cases of carotid dissection revealed by isolated paralysis of the ipsilateral half tongue. . First patient, 52 years old, with no particular medical or surgical history, presented with isolated paralysis of the left half tongue preceded by two weeks of moderate-intensity cervicalgia and having been the subject to cervical manipulation.

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Background: Area postrema syndrome (APS) is considered to be one of the most specific clinical presentations of neuromyelitis optica spectrum disorders (NMOSDs). In sub-Saharan Africa, NMOSDs and even more so those revealed by an APS, are rarely reported. However, studies among mixed populations have shown that NMOSDs disproportionately affect black people with relatively more frequent encephalic involvement.

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Background: Encephalitis of Rasmussen is an inflammatory hemiencephalopathy of unknown etiology. It is a cause of drug-resistant epilepsy.

Aim: To report two cases of Rasmussen's encephalitis (RE) in a low-income setting.

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Neuromyelitis optica (NMO) appears to affect blacks disproportionately in mixed populations. We report the first case of documented NMO in Togo (West Africa). A 26-year-old Togolese woman was admitted for progressive tetraplegia, acute urine retention, and dyspnea.

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Myasthenia gravis is a rare acquired autoimmune pathology causing neuromuscular transmission impairment. Juvenile onset of myasthenia gravis is often characterized by ocular involvement. We report two cases of ocular juvenile myasthenia gravis (JMG) in two siblings.

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Background: Guillain-Barré syndrome (GBS) has been reported to be associated with Zika virus (ZIKV) infection in case reports and retrospective studies, mostly on the basis of serological tests, with the problematic cross-reacting antibodies of the Flavivirus genus. Some GBS cases do not exhibit a high level of diagnostic certainty. This prospective study aimed to describe the clinical profiles and the frequency of GBS associated with ZIKV during the ZIKV outbreak in Martinique in 2016.

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We report two cases of encephalopathy (one with seizures, one with electroencephalogram changes) in patients with Zika virus infection. The cases occurred on Martinique in February 2016, during the Zika virus outbreak. Awareness of the various neurological complications of Zika virus infection is needed for patients living in areas affected by Zika virus infections or for travellers to these areas.

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We report two cases of Guillain-Barré syndrome who had concomitant Zika virus viruria. This viruria persisted for longer than 15 days after symptom onset. The cases occurred on Martinique in January 2016, at the beginning of the Zika virus outbreak.

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Background: Convulsive seizures are the common neurological emergencies in developing regions.

Objectives: The aim was to determine the prevalence, causes and outcome of seizures in childhood.

Patients And Methods: Participants were children aged 1-5 years old, admitted consecutively with a history of febrile convulsions or were presented seizures with fever during hospitalization, in two pediatric university hospitals.

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Unlabelled: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that causes damage of upper motor neuron and lower motor neuron. Our objective was to describe the incidence and demographic characteristics of ALS and to analyze its diagnosis and management in Togo.

Materials And Methods: A retrospective and descriptive study of patient's observations was conducted in the department of neurology of the teaching hospital in Lomé during a 10 years period (2000 to 2009).

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Some authors have suggested that the syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) results from an immunological response directed against a viral agent. Here we report a case of HaNDL in an immunocompetent 19-year-old male that could support this hypothesis.

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Background/aims: The Solitaire stent has been suggested as a promising device to perform intracranial thrombectomy in large vessels. We report our experience.

Methods: Consecutive patients in whom a thrombectomy with Solitaire stent had been performed for acute ischemic stroke in the Lyon Stroke Unit, France, from November 2009 to November 2010 were enrolled.

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The objective of this study is to determine the main opportunistic infections (OI) and those strongly linked to high death rate in hospital settings in Togo. It is a descriptive study conducted from June to November 2008 in 22 public and private settings of all medical specialties throughout the entire Togolese territory. Hospitalized patients with OI and HIV positive data were collected.

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The financial crisis that affected the healthcare systems of most developing countries in the 1980s, the ensuing need to control hospital costs, the partial disengagement of States, and the resort to policies based on cost recovery -- all these led to the restructuring of hospital systems in Africa, in accordance with the Bamako initiative, adopted by the WHO regional committee in September 1987. This restructuring required populations to pay much of the cost of their health care. In practice, however, the major obstacle to this policy of cost recovery remains poverty.

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Epilepsy, the most common serious neurological condition, is one of the most widespread non-transmissible diseases in the world. In developing countries, about 90% of those with epilepsy do not receive appropriate treatment; this treatment gap, very high compared with other chronic diseases, helps to explain the marginalisation and poor living conditions of these people. Reducing this treatment gap and the burden that epilepsy represents is a difficult task and the obstacles are numerous.

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