Turner syndrome transition clinic in the West of Scotland: a perspective.

Introduction: Turner Syndrome (TS) is the commonest chromosomal abnormality in females. Establishing and maintaining long-term follow-up after transition to adult endocrine services, to allow for essential lifelong surveillance of hypertension and cardiovascular disease, and optimal hormone replacement, remains a challenge. A TS transition clinic was established with the aim of supporting successful transfer and establishing long-term follow-up in adult endocrine services.

Evaluating transition in Turner syndrome in the West of Scotland.

Background: A Turner Syndrome (TS) Transition clinic, Royal Hospital for Children Glasgow (RHCG), with paediatric and adult endocrinology/gynaecology teams was established in 1998 with an aim of improving health outcomes in TS throughout the lifespan.

Objective: To evaluate the success of our TS transition service, focussing on evaluating established follow-up after transfer to adult services.

Methods: Girls attending the TS Transition clinic at Royal Hospital for Children Glasgow, 1998-2017, were identified.

Relationship of body fat and its distribution with bone mineral density in Indian population.

Obesity has been associated with increased bone mineral density (BMD). There is evidence of differential effect of regional fat on BMD. Hence, we undertook this study to evaluate the correlation between total body fat and its distribution with BMD in nonobese (mean body mass index: 25.

Reference range of thyroid function (FT3, FT4 and TSH) among Indian adults.

Objectives: To generate thyroid hormone reference norms using electro-chemiluminescence technique.

Design And Methods: Cross sectional study on apparently normal 4349 Delhi adults (18-86 years). Predetermined exclusion criteria (goiter, hypoechogenicity or nodularity on ultrasound, elevated anti-thyroid peroxidase antibody, hypo or hyperthyroidism and family history of thyroid dysfunction) excluded 2433 subjects leaving 1916 (916 males and 1000 females) as the reference population.

Status of thyroid function in Indian adults: two decades after universal salt iodization.

Objectives: The aim was to find impact of two decades of universal salt iodization on the prevalence of goiter, thyroid autoimmunity and thyroid dysfunction in Indian adults.

Methods: This was a cross sectional study from Delhi, India. The subject population included 4409 adult members of resident welfare associations of 5 residential colonies, from 18-90 years of age, who participated in general health check-up camps.

The evolution of thyroid function with puberty.

Objective: This study was planned to describe thyroid functional status in different stages of puberty.

Study Design: We collected data from five schools across different geographical zones of Delhi. All children who consented were evaluated for anthropometry, pubertal stage, goitre status, serum free T3 (FT3), free T4 (FT4), TSH, anti-TPO (thyroid peroxidase) antibodies and thyroid ultrasound.

Establishment of age-specified bone mineral density reference range for Indian females using dual-energy X-ray absorptiometry.

We undertook this study to establish age-specified bone mineral density (BMD) reference range for Indian females using dual-energy X-ray absorptiometry. BMD at multiple skeletal sites was measured in 2034 healthy women aged 18--85yr. The effect of anthropometry and biochemical parameters on BMD was determined.

Thyroid status two decades after salt iodization: country-wide data in school children from India.

Objective: Country-wide evaluation of thyroid disorders in school children following two decades of universal salt iodization (USI) has not been carried out till date. This study was planned with aim to assess thyroid status of school children two decades after the launch of USI programme.

Design: Population survey.

Reference intervals of serum lipid profile in healthy Indian school children and adolescents.

Objective: To develop age and sex specific reference intervals of serum lipid parameters in healthy Indian children in the age group of 6-17 years.

Participants: Study subjects were selected from the schools of Delhi. Children with BMI either in overweight or obese category were excluded to generate reference intervals.

Hypovitaminosis d and hypocalcemic seizures in infancy.

Background: Hypocalcemia accounts for a majority of seizures in infants reporting to the emergency ward of our hospital.

Objective: To evaluate the role of Vitamin D deficiency in the etiology of hypocalcemic seizures in infancy.

Design And Setting: Cross sectional hospital based study, from April 2006-March 2007.

Reference range of thyroid hormones in healthy school-age children: country-wide data from India.

Objective: This study was planned to obtain normative data of thyroid functions in school-age children from different regions of India.

Design And Methods: Students from 36 schools involving 13 states across four geographical zones of India were evaluated for goiter. Subjects who consented, underwent evaluation for serum FT3, FT4, TSH, anti-TPO antibodies and thyroid ultrasound.

Reference range of thyroid hormones in normal Indian school-age children.

Objective: There is an ongoing debate on narrowing the TSH reference range in adults. In view of the scarce data on normal values of thyroid function tests in children from India, we planned to establish a reference range for thyroid hormones in school-age children.

Design And Subjects: All children (N = 9527; 6-19 years) from six schools representing various zones of Delhi were evaluated for clinical evidence of goitre, thyroid ultrasound, serum free T3 (FT3), free T4 (FT4) and TSH and anti-thyroid peroxidase (anti-TPO) antibodies.