Publications by authors named "Apanasenko Z"

After the 7-day space flight of Cosmos-1667 the reproductive system of white rats was investigated. No differences between the flight rats and synchronous and vivarium controls were detected with respect to such parameters as the testis and epididymis weight, testicular content of spermatogonia, spermatocytes, spermatids, spermatozoa, Leydig's cells and Sertoli's cells, and the number of normal and atypical spermatozoa in the epididymis. Nuclei of Sertoli's cells were similar in size in the flight and control rats.

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The Wistar female rats were flown on the biosatellite Cosmos-1514 during their pregnancy days 13-18. Offspring (at the age 1 to 3 months) of four of these rats were used to investigate their behavioral reactions in the open field and mazes of different design, food attraction being applied. Control rats of matched pregnancy term were kept either in a vivarium or in a biosatellite mockup where all flight factors, except for weightlessness, were simulated.

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Changes of conditioned reflexes were analyzed in albino rats during their 18.5 days on board the "Cosmos-1129" bio-satellite. With total lowering of the level of conditioned activity, the most affected proved to be reactions linked with internal inhibition; differentions were disinhibited, the number of intersignal reactions significantly exceeded control values.

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Male rats that were flown for 18.5 days on Cosmos-1129 were mated postflight with intact females. The mating 5 days postflight when the ejaculate consisted of spermatozoids that were exposed to zero-g effects in the mature stage yielded the litter which lagged behind the controls with respect to the growth and development during the first postnatal month.

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A study was made of the behaviour of albino rats solving complex tasks in the Lachman maze and in a maze of original design, on the 18th to 24th days after exposure on board the "Kosmos-936" biosatellite. In conditions of artificial gravitation the animals solved such tasks significantly worse than those which were not subjected to centrifugation on board. Control trials on Earth and some features of the experimental technique suggest that this fact is due to negative influence of angular velocities during centrifugation on the animal's central nervous system.

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The recovery of a goal-reaching habit (food reaching) was studied in albino rats in a maze after space exposure on biosatellite "Kosmos-936". Animals which were exposed to artificial gravitation during the flight, restored the habit slightly worse than those not centrifuged. The tendency toward worsening is clearly pronounced, although the small number of animals and small changes (which to a considerable degree was due to relatively simple tasks) seem to produce insignificant differences at this stage of the study.

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Maze behaviour of rats was studied on 6--25th days after exposure on biosatellite "Kosmos-782". Presentation of a foreign stimulus (a bell) on the 6--7th day after return, had a weaker effect on the maze performance in experimental rats, than in the control group. The experimental animals were also better adapted, as compared to the control ones, to an increased functional stress on CNS (increased number of runs in the maze from 3 to 16 in one session), applied on 11--13th day after the return.

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The retention and recovery of food-procuring skill in the maze was impaired in rats after 19.5-days space flight. The study conducted 2--12 days after landing, revealed an increase in the number of erroneous movements and of refusals to cope with the maze, as well as in the time of reaching the goal.

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Rats irradiated aboard the biosatellite Cosmos-690 and in the synchronous mockup showed deteriorated retention and recovery of the skill of traversing the maze. The rats irradiated on the Earth displayed greater changes in the parameters. The rats irradiated inflight exhibited an increased fatigue during enhanced activity.

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During the period from the 15th to the 50th day after the end of the flight in the "Cosmos-605" biosatellite, the rats revealed a deterioration of the capacity for the transfer of experience and for improving the habit of reaching the goal in a maze. There was also a change in the dynamics of errors during the experiment which testifies to greater susceptibility to exhaustion of nervous processes. Some parameters indicated a tendency to normalization of higher nervous activity.

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Functional changes of higher nervous activity were found in the rats after a 22-day flight in the biosatellite "Cosmos-605". The ability to retain and restore the habit of searching food in the maze deteriorated. The number of refusals to go through the maze increased with an enhancement of the functional load on the central nervous system.

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