Publications by authors named "Aoxuan Xu"
Biomol Biomed
September 2024
Article Synopsis
- This study investigates the role of lncRNA MALAT1 in Hypopharyngeal Squamous Cell Carcinoma (HSCC) and its mechanisms, finding that MALAT1 is significantly upregulated in cancerous tissues and linked to poor patient outlook.
- Researchers utilized various techniques like qRT-PCR and Cox regression analysis to confirm that MAP2K1 is a key downstream target affected by MALAT1, impacting tumor behavior.
- Experiments demonstrated that inhibiting MALAT1 could suppress HSCC cell proliferation, migration, and tumor growth by downregulating MAP2K1, suggesting that targeting MALAT1 might provide new treatment strategies for HSCC.
