Publications by authors named "Aowen Liu"
Article Synopsis
- There is growing interest in using postbiotics from sourdough strains to tackle obesity and related gut issues, particularly focusing on their impact on zebrafish with a high-fat diet.
- The study evaluated different preparation methods for these postbiotics, finding that heat-killing at 120 °C was the most effective, leading to various health benefits such as reducing weight gain and intestinal inflammation in zebrafish.
- Results showed differences in health effects among the postbiotics, with K-LP25 being effective for weight management and inflammation reduction, while K-PP18 was better at preventing gut barrier damage, suggesting that sourdough-derived postbiotics could be promising for gut health interventions.
The development and outcome of inflammatory diseases are associated with genetic and lifestyle factors, which include chemical and nonchemical stressors. Persistent organic pollutants (POPs) are major groups of chemical stressors. For example, dioxin-like polychlorinated biphenyls (PCBs), per- and polyfluoroalkyl substances (PFASs), and polybrominated diphenyl ethers (PBDEs) are closely associated with the incidence of inflammatory diseases.
View Article and Find Full Text PDFOligonucleotides (OGNs) are relatively new modalities that offer unique opportunities to expand the therapeutic targets. Reliable and high-throughput bioanalytical methods are pivotal for preclinical and clinical investigations of therapeutic OGNs. Liquid chromatography-mass spectrometry (LC-MS) is now evolving into being the method of choice for the bioanalysis of OGNs.
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