Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms.

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects approximately 0.46% of the global population. Conventional therapeutics for RA, including disease-modifying antirheumatic drugs (DMARDs), nonsteroidal anti-inflammatory drugs (NSAIDs), and corticosteroids, frequently result in unintended adverse effects.

Lower limbs micro-loading acutely attenuates repeated change-of-direction performance in male youth during small-sided soccer games.

Background: Soccer players often wear light-weighted wearable resistance (WR) attached to different body parts during the warm-up period with the aim to improve measures of physical fitness. However, the effect of WR on physical performance is unknown. This study evaluated the effects of WR with different micro-loadings on repeated change-of-direction (RCoD) performance while executing small-sided soccer games (SSG).

A 10-week FIFA 11+ program improves the short-sprint and modified agility T-test performance in elite seven-a-side soccer players.

The primary objective of this study was to assess the effects of 10 weeks of FIFA 11+ training on the physical performance of elite seven-a-side soccer players. Twenty-five seven-a-side soccer players were recruited from two senior national teams. The players completed the following protocols during 10 weeks of training: a) FIFA 11+: The FIFA group ( = 13) underwent the FIFA 11+ program combined with regular soccer training; b) Dynamic conventional warm-up: The control group ( = 12) underwent regular soccer training.

Acute Effect of Four Stretching Protocols on Change of Direction in U-17 Male Soccer Players.

Background: The ability to rapidly change direction while sprinting is a desirable athletic skill in soccer. Enhancing change of direction (COD) performance depends almost exclusively on specific training, with stretching traditionally considered one such intervention. However, the comparative impact of diverse stretching methods on COD in soccer players remains an area of interest.

Postural profile of female basketball players and differences among playing positions.

Objective: Basketball players often display poor balance and increased injury rates when compared to other athletic categories. Therefore, the relationship between postural control and injury risks in basketball athletes requires investigation. The purpose of this study was to: (a) establish a postural profile of elite women basketball players, (b) compare postural control of the different playing positions to detect the vulnerability of postural balance, and (c) attempt to understand the reasons underlying these differences.

Effects of Endurance Training Intensity on Pulmonary Diffusing Capacity at Rest and after Maximal Aerobic Exercise in Young Athletes.

This study compared the effects of varying aerobic training programs on pulmonary diffusing capacity (TL), pulmonary diffusing capacity for nitric oxide (TL), lung capillary blood volume (Vc) and alveolar-capillary membrane diffusing capacity (DM) of gases at rest and just after maximal exercise in young athletes. Sixteen healthy young runners (16-18 years) were randomly assigned to an intense endurance training program (IET, = 8) or to a moderate endurance training program (MET, = 8). The training volume was similar in IET and MET but with different work intensities, and each lasted for 8 weeks.

Effects of Unloaded vs. Ankle-Loaded Plyometric Training on the Physical Fitness of U-17 Male Soccer Players.

The aim of this study was to compare the impact of two differing plyometric training programs (loaded plyometrics (with 2.5% of body mass placed above the ankle joint) vs. unloaded plyometrics), performed biweekly for 10 weeks, on the physical fitness of elite junior male soccer players.

The effect of a sand surface on physical performance responses of junior male handball players to plyometric training.

Background: The effects of 7 weeks plyometric training on a stable surface and on sand were compared in junior male handball players.

Methods: A team of experienced players was divided randomly between three groups, undertaking a standard in-season regimen (C,  = 10), or supplementing this regimen by plyometric training on sand (PS,  = 11) or a stable surface (P, n = 10) for 7 weeks. Assessments included 20 m sprint times, change of direction tests (Modified change-of-direction T-test and Modified Illinois test), a repeated sprint T-test, jumping ability (squat, countermovement and five jump tests), and static and dynamic balance.

Effects of an In-season Plyometric Training Program on Repeated Change of Direction and Sprint Performance in the Junior Soccer Player.

Hammami, M, Negra, Y, Aouadi, R, Shephard, RJ, and Chelly, MS. Effects of an in-season plyometric training program on repeated change of direction and sprint performance in the junior soccer player. J Strength Cond Res 30(12): 3312-3320, 2016-We aimed to determine the gains in explosive movements of male junior soccer players induced by incorporating an 8-week plyometric training program (PTP) into a standard soccer conditioning regimen 5 months after the beginning of the competitive season.

Relationships between the yo-yo intermittent recovery test and anaerobic performance tests in adolescent handball players.

The aim of the present study was to investigate relationships between a performance index derived from the Yo-Yo Intermittent Recovery Test level 1 (Yo-Yo IR1) and other measures of physical performance and skill in handball players. The other measures considered included peak muscular power of the lower limbs (Wpeak), jumping ability (squat and counter-movement jumps (SJ, CMJ), a handball skill test and the average sprinting velocities over the first step (VS) and the first 5 m (V5m). Test scores for 25 male national-level adolescent players (age: 17.

Validity and reliability of new agility test among elite and subelite under 14-soccer players.

Background: Agility is a determinant component in soccer performance. This study aimed to evaluate the reliability and sensitivity of a "Modified Illinois change of direction test" (MICODT) in ninety-five U-14 soccer players.

Methods: A total of 95 U-14 soccer players (mean ± SD: age: 13.

Effects of 8-week in-season plyometric training on upper and lower limb performance of elite adolescent handball players.

We hypothesized that replacement of a part of the normal in-season regimen of top-level adolescent handball players by an 8-week biweekly course of lower and upper limb plyometric training would enhance characteristics important to competition, including peak power output (Wpeak), jump performance, muscle volume, and ball throwing velocity. Study participants (23 men, age: 17.4 ± 0.

Effects of a shoot training programme with a reduced hoop diameter rim on free-throw performance and kinematics in young basketball players.

The present paper investigated the effects of a shoot training programme with a reduced hoop diameter (0.35 m) rim on kinematics and performance of basketball free-throws. Eighteen young male basketball players were divided into control (CG, n = 9) and experimental (EG, n = 9) groups.

Association of anthropometric qualities with vertical jump performance in elite male volleyball players.

Aim: The objective of this study was to examine the association between physical and anthropometric profiles and vertical jump performance in elite volleyball players.

Methods: Thirty-three elite male volleyball players (21±1 y, 76.9±5.

Aerobic training programs and glycemic control in diabetic children in relation to exercise frequency.

Aim: The aim of this study was to assess the effect of an aerobic training on glycemic control and lipid profile in diabetic children.

Methods: Thirty-three children with type 1 diabetes mellitus (T1DM) were equally divided in three groups. The control group (CG) did not perform any training intervention during the period of the investigation and the subjects were instructed to continue with their daily lifestyle patterns.

Match analysis of elite adolescent team handball players.

The purposes of this study were to examine the activity profile of elite adolescent players during regular team handball games and to compare the physical and motor performance of players between the first and second halves of a match. Activity patterns (video analysis) and heart-rate (HR) responses (telemetry) were monitored in top national-division adolescent players (18 men, aged 15.1 ± 0.

Effects of a plyometric training program with and without added load on jumping ability in basketball players.

The purpose of this investigation was to examine the effect of a standard plyometric training protocol with or without added load in improving vertical jumping ability in male basketball players. Twenty-seven players were randomly assigned to 3 groups: a control group (no plyometric training), plyometric training group (PG), and loaded plyometric group (LPG, weighted vests 10-11% body mass). Before and after the 10-week training program, all the players were tested for the 5-jump test (5JT), the squat jump (SJ), and the countermovement jump (CMJ).

[Biologic profile in Tunisian infants (0-2 years), malnourished].

Background: The malnutrition of the infants could be explained by a delay of the growth and the perturbation of biological parameters.

Aim: To establish the nutritional profile of the Tunisian infant of less than two years. To specify the principal deficiencies and the possible origins of these deficiencies.