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Publications by authors named "Aoting Gu"

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CRISPR/Cas12a and Hybridization Chain Reaction-Coregulated Magnetic Relaxation Switching Biosensor for Sensitive Detection of Viable in Animal-Derived Foods.
Aoting Gu Yongzhen Dong Letian Li Deyang Yu Jiangjiang Zhang

J Agric Food Chem

September 2024

We combined a CRISPR/Cas12a system with a hybridization chain reaction (HCR) to develop an ultrasensitive magnetic relaxation switching (MRS) biosensor for detecting viable (). Magnetic nanoparticles of two sizes (30 and 1000 nm: MNP and MNP, respectively) were coupled through HCR. The gene-activated CRISPR/Cas12a system released MNP from the MNP-HCR-MNP complex through a trans-cleavage reaction.

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