Construction of Self-healing Active Centers over Amorphous NiFe(OH) Nanosheets for Enhanced Oxygen Evolution Performance.

Developing efficient nickel-iron-based electrocatalysts for the oxygen evolution reaction (OER) still remains a challenge for long-term application in water electrolysis. Herein, amorphous NiFe hydroxide nanosheets with self-healing active centers supported on stainless steel mesh (-NiFe(OH)/SSM) are fabricated using a simple electrochemical deposition strategy. Raman evidence shows that the amorphous structure of -NiFe(OH)/SSM exhibits strong self-healing ability, efficiently promoting the rapid interconversion between the γ-NiOOH intermediate and Ni-based hydroxides during electrocatalysis.

Role of 3-mercaptopyruvate sulfurtransferase in cancer: Molecular mechanisms and therapeutic perspectives.

The occurrence and development of tumor is mediated by a wide range of complex mechanisms. Subsequent to nitric oxide and carbon monoxide, hydrogen sulfide (HS) holds the distinction of being the third identified gasotransmitter. Alternation of HS level has been widely demonstrated to induce an array of disturbances in important cancer cell signaling pathways.

Hydrogen Sulfide in Musculoskeletal Diseases: Molecular Mechanisms and Therapeutic Opportunities.

Musculoskeletal diseases seriously affect global health, but their importance is greatly underestimated. These diseases often afflict the elderly, leading to disability, paralysis, and other complications. Hydrogen sulfide (HS) plays an important role in the occurrence and development of musculoskeletal diseases, which may have potential therapeutic significance for these diseases.

The Emerging Roles of Hydrogen Sulfide in Ferroptosis.

Ferroptosis, a form of regulated cell death characterized by a large amount of lipid peroxidation-mediated membrane damage, joins the evolution of multisystem diseases, for instance, neurodegenerative diseases, chronic obstructive pulmonary disease, acute respiratory distress syndrome, osteoporosis, osteoarthritis, and so forth. Since being identified as the third gasotransmitter in living organisms, the intricate role of hydrogen sulfide (HS) in ferroptosis has emerged at the forefront of research. Novel targets in the relevant metabolic pathways have been found, including transferrin receptor 1, cystine/glutamate antiporter, and others, coupled with the exploration of new signaling pathways, particularly the p53 signaling pathway, the nitric oxide/nuclear factor erythroid 2-related factor 2 signaling pathway, and so on.