Publications by authors named "Aoife O'Carroll"

Epilepsy is a neurological condition characterised by recurrent and persistent seizures. For paediatric patients, achieving early seizure freedom can have positive impacts on cognition, development, social integration and mental health, leading to improved quality of life. In general, one third of patients with epilepsy are refractory to medication; for these patients, epilepsy surgery may offer the only chance for improved seizure control.

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Article Synopsis
  • Researchers wanted to see how REM sleep affects seizures in people with epilepsy.
  • They looked at EEG recordings to measure how long REM sleep lasted and how often abnormal brain activity happened during REM.
  • They found that more abnormal activity in REM was linked to having more seizures, which could help doctors understand how a person's epilepsy might progress.
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Background: Medical students face an information-rich environment in which retrieval and appraisal strategies are increasingly important.

Objective: To describe medical students' current pattern of health information resource use and characterize their experience of instruction on information search and appraisal.

Methods: We conducted a cross-sectional web-based survey of students registered in the four-year MD Program at Dalhousie University (Halifax, Nova Scotia, and Saint John, New Brunswick, sites), Canada.

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Cancer patients at the end of life often take many medications and are at risk for drug interactions. The purpose of this study was to describe the epidemiology of potential drug interactions in cancer patients receiving supportive care exclusively. We retrospectively reviewed the charts of consecutive adult cancer outpatients attending palliative care clinics at the Princess Margaret Hospital, Toronto, Canada.

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Purpose: There is concern that financial relationships between sponsors and investigators may bias research results. Our objective was to evaluate the epidemiology of conflicts of interest (COIs) among authors of clinical trials and editorials in oncology and the relationship between COI disclosure and source of funding.

Methods: We did a cross-sectional survey of clinical trials and editorials of anticancer agents and supportive care medications published in the Journal of Clinical Oncology (JCO) during a 1-year period.

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Background: Patients with advanced cancer frequently experience distressful symptoms and receive numerous medications. We describe the symptomatology and medication profile of ambulatory cancer patients receiving exclusively supportive care at the Princess Margaret Hospital.

Materials And Methods: This was a retrospective, cross-sectional study.

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Objectives: We described morphologic characteristics, particularly pulmonary anatomy, and determined the prevalence of definitive end states and their determinants in children with pulmonary atresia associated with ventricular septal defect (PAVSD).

Background: Pulmonary atresia associated with ventricular septal defect represents a broad morphologic spectrum that greatly influences management and outcomes.

Methods: From 1975 to 2004, 220 children with PAVSD presented to our institution.

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