Site-selective iodine atom transfer in fluorinated alkyl iodides 1,5-hydrogen atom transfer.

The direct and selective functionalization of inert C-H bonds intramolecular hydrogen atom transfer (HAT) is an increasingly powerful tool in organic synthesis. Herein, we designed an efficient and facile iodine atom transfer in fluorinated alkyl iodides 1,5-HAT. Our process enables site-selective iodination of unreactive C(sp)-H bonds to afford di- and tri-fluorinated alkyl iodides in good yields.