Publications by authors named "Aoi Fujiwara"

Aim: Recently, a new technique using attenuation imaging (ATI) was developed to diagnose hepatic steatosis. The aim of this study was to investigate whether ATI for the evaluation of hepatic steatosis is influenced by liver fibrosis.

Methods: A total of 328 patients with chronic liver disease were enrolled to study the associations between histological hepatic steatosis or liver fibrosis and ATI findings.

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The indications for immune checkpoint inhibitors (ICIs) have expanded to include carcinomas of various organs. However, as ICI therapy expands, the management of immune-related adverse events (irAEs) has become a problem. ICI-related pancreatitis and cholangitis are relatively rare irAEs.

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Background/aim: A new scoring system [albumin-bilirubin-platelet (ALBI-PLT) score] was reported for identifying cirrhotic patients without high-risk varices (HRV), and patients with ALBI grade 1 (≤-2.60) and a platelet count over 150×10/l were shown to have a low risk of having HRV. The present study modified the cut-off values of the variables in the ALBI-PLT score.

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Background/aim: Recent advances in antiviral treatment have achieved a sustained viral response (SVR) in over 95% of hepatitis C virus (HCV) infections. HCV elimination is suggested to improve several lifestyle-related factors; however, few studies have focused on dietary habit-/appetite-related factors.

Patients And Methods: HCV-infected patients who received Daclatasvir/Asnaprevir (DCV/ASV) therapy were enrolled, and the changes in appetite-related molecules after antiviral therapy were assessed with a multiple cytokine-measuring system.

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Article Synopsis
  • * Initial imaging raised concerns for metastatic liver tumors, but further tests ruled out malignancy and confirmed the diagnosis of IPT through a biopsy showing characteristic cell shedding and inflammation.
  • * The case highlights the importance of thorough evaluation using various imaging techniques to avoid misdiagnosis when encountering multiple liver tumors.
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Aim: The pathogenic process underlying the development of hepatocellular carcinoma (HCC) is not yet clear in patients with chronic hepatitis C virus who receive direct-acting antiviral therapy and achieve sustained virological response. This study investigated two risk factors for HCC in these patients; specifically, hepatic fibrosis and steatosis.

Methods: A total of 355 patients in whom hepatitis C virus was eradicated by direct-acting antiviral were evaluated.

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