Synopsis of recent research by authors named "Aohan Guan"
- Aohan Guan's recent research focuses on the intersection of genetics, virology, and immunology, utilizing innovative methodologies to explore biological processes in prokaryotic systems and animal models, particularly in high-altitude environments and viral dynamics.
- Key findings include the development of 3D-GeneNet for better understanding of gene association networks based on spatial proximity, insights into the gut virome of Tibetan pigs relating to their development at high altitudes, and an efficient phylogenetic estimation tool for viruses named Bd-RPC that addresses emerging infectious diseases.
- Additionally, Guan's work highlights the role of resistin in endothelial dysfunction during infections and presents the molecular cloning of duck TYK2, shedding light on avian immune responses, which are vital for the understanding of disease mechanisms and potential therapeutic targets.