The role of remifentanil in regulating mitochondrial autophagy in osteoclasts was investigated based on PINK1/Parkin pathway.

This study aimed to explore the regulatory effect of remifentanil-mediated mitochondrial autophagy on osteoclast formation and further investigate its mechanism. Macrophage cell line RAW264.7 was taken and induced to differentiate into mature osteoclasts using nuclear factor kB receptor activating factor ligand (RANKL).

Diatom Cribellum-Inspired Hierarchical Metamaterials: Unifying Perfect Absorption Toward Subwavelength Color Printing.

Diatom exoskeletons, known as frustules, exhibit a unique multilayer structure that has attracted considerable attention across interdisciplinary research fields as a source of biomorphic inspiration. These frustules possess a hierarchical porous structure, ranging from millimeter-scale foramen pores to nanometer-scale cribellum pores. In this study, this natural template for nanopattern design is leveraged to showcase metamaterials that integrates perfect absorption and subwavelength color printing.

In-hospital outcomes in metabolically healthy and unhealthy individuals over 65 years of age with obesity undergoing percutaneous intervention for acute coronary syndrome: A nationwide propensity-matched analysis (2016-2020).

Background: The obesity paradox in patients with coronary artery disease is well established, but the role of the metabolic syndrome associated with obesity is not well studied. Our study aims to evaluate the in-hospital outcomes of percutaneous coronary intervention (PCI) in metabolically healthy individuals with obesity (MHO) and metabolically unhealthy (MUHO) individuals with obesity over 65 years of age with acute coronary syndrome (ACS) between 2016 and 2020.

Methods: This was a retrospective and observational study.

Does Statin Use in Frail Patients Provide Survival Benefits? Insights From a Meta-Analysis.

Frailty is a complex syndrome that increases with age and predisposes older adults to adverse outcomes, including mortality. Statins are proven to lower the risk of atherosclerotic cardiovascular disease, but there is limited data on their survival benefit in frail older people. This meta-analysis was conducted to determine whether statins can lower mortality in frail persons.

Time-moduated nonreciprocal metasurface absorber for surface waves.

We have investigated a magnet-free, nonreciprocal surface wave absorber based on high impedance surfaces (HISs) using a spatial-temporal modulation approach. By controlling embedded switches with a travelling wave, the HIS metasurface is modulated to break the time and spatial symmetry, which enables surface waves to propagate in one direction but be absorbed when propagating in the reverse direction. The nonreciprocity has been demonstrated by an EM-circuit co-simulation.

Integrating microsystems with metamaterials towards metadevices.

Electromagnetic metamaterials, which are a major type of artificially engineered materials, have boosted the development of optical and photonic devices due to their unprecedented and controllable effective properties, including electric permittivity and magnetic permeability. Metamaterials consist of arrays of subwavelength unit cells, which are also known as meta-atoms. Importantly, the effective properties of metamaterials are mainly determined by the geometry of the constituting subwavelength unit cells rather than their chemical composition, enabling versatile designs of their electromagnetic properties.

Optical homogeneity measurement of parallel plates by wavelength-tuning interferometry using nonuniform fast Fourier transform.

Wavelength-tuning interferometry is commonly employed to measure the optical homogeneity of parallel plates. However, the nonlinearity of phase shifts caused by wavelength tuning errors and environmental vibration leads to a spatially uniform error in the calculated phase distribution. Herein, a wavelength-tuning interferometry method based on nonuniform fast Fourier transform (WTI-NUFFT) was developed, which solves the spectral aliasing resulting from the spatially uniform error.

Plasmonic heating induced by Au nanoparticles for quasi-ballistic thermal transport in multi-walled carbon nanotubes.

The plasmon resonances of nanostructures enable wide applications from highly sensitive sensing to high-resolution imaging, through the improvement of photogeneration rate stimulated by the local field enhancement. However, quantitative experimental studies on the localized heating and the thermal transport process in the vicinity of plasmonics are still lacking because of the diffraction limit in conventional optothermal methodologies. In this work, we demonstrate an approach based on Raman thermometry to probe the near-field heating caused by plasmonics.

Implementing infrared metamaterial perfect absorbers using dispersive dielectric spacers.

A typical metamaterial perfect absorber (MPA) is comprised of a metamaterial layer, a dielectric spacer, and a ground plane. The conventional spacer material is usually a lossy dielectric with little-dispersion for the purpose of easing the design and optimization procedure of the MPA. In this paper, we present the design, fabrication, and characterization of metamaterial perfect absorbers with a highly dispersive spacer, which is compatible with functional microelectromechanical systems.

Silica Nanowire Growth on Coscinodiscus Species Diatom Frustules via Vapor-Liquid-Solid Process.

Diatom frustules are a type of porous silicon dioxide microparticle that has long been used in applications ranging from biomedical sensors to dye-sensitized solar cells. The favorable material properties, enormous surface area, and enhanced light scattering capacity support the promise of diatom frustules as candidates for next generation biomedical devices and energy applications. In this study, the vapor-liquid-solid (VLS) method is employed to incorporate silica nanowires on the surface of diatom frustules.

Trimetazidine suppresses oxidative stress, inhibits MMP-2 and MMP-9 expression, and prevents cardiac rupture in mice with myocardial infarction.

Background/aims: Cardiac rupture (CR) is a catastrophic complication of acute myocardial infarction (MI). At present, there are no effective pharmacological strategies for preventing post-MI rupture. Here we investigated the effect of trimetazidine (TMZ) on post-MI CR.

Safety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction: A meta-analysis of randomised controlled trials.

Background Early discharge after successful primary angioplasty is common, but the evidence supporting the practice is still lacking. We therefore performed a meta-analysis assessing the safety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction (STEMI). Methods Randomised controlled trials were identified and extracted from PubMed, Embase, Cochrane Library databases and reference lists of relevant papers.

Beta-blockers reduced the risk of cardiac rupture in patients with acute myocardial infarction: A meta-analysis of randomized control trials.

Background: Cardiac rupture (CR) is a catastrophic complication that occurs after acute myocardial infarction (MI) and, at present, there are no effective pharmacological strategies for preventing this condition. The objective of this meta-analysis was to assess the effect of beta-blockers on CR in patients with acute MI.

Methods: An extensive search of the PUBMED, EMBASE, ISI Web of Science, MEDLINE and Cochrane was performed to retrieve the studies of beta-blockers treatment in patients with acute MI.

Towards uniformly oriented diatom frustule monolayers: Experimental and theoretical analyses.

Diatoms are unicellular, photosynthetic algae that are ubiquitous in aquatic environments. Their unique, three-dimensional (3D) structured silica exoskeletons, also known as frustules, have drawn attention from a variety of research fields due to their extraordinary mechanical properties, enormous surface area, and unique optical properties. Despite their promising use in a range of applications, without methods to uniformly control the frustules' alignment/orientation, their full potential in technology development cannot be realized.

Experimental study of the interaction between DC discharge microplasmas and CW lasers.

A high power (~ 1W) continuous wave (CW) laser was focused on argon microplasma generated in the microgap between two electrodes with submillimeter diameters. Dependence of breakdown (V(BD)) and quench (V(Q)) voltages of microplasma to the laser power, wavelength, and spot location were studied as the gap size and pressure varied. It was observed that the laser-plasma interaction can only occur thermally through the electrodes.

Culture and motion analysis of diatom Bacillaria paradoxa on a microfluidic platform.

We proved the feasibility of using a microfluidic chip to culture diatom Bacillaria paradoxa, and analyzed the gliding characteristics of its self-organized colony in detail. The optimal cultivation parameters of B. paradoxa for the designed chip made with polydimethylsiloxane are as follows: the preferable cells injecting rate for keeping the cells alive is 0.

Biosilica structures obtained from Nitzschia, Ditylum, Skeletonema, and Coscinodiscus diatom by a filtration-aided acid cleaning method.

A filtration-aided acid cleaning method was used to collect biosilica structures from a diatom culture medium, natural seawater, or water bloom. Cell extraction, acid cleaning, and acid removal were all performed on a polytetrafluoroethylene (PTFE) filter cloth, significantly improving the treatment capacity and efficiency of the traditional acid wash method. Five typical diatoms were cultivated in the laboratory for acid cleaning.