Patterns and Drivers of Surface Energy Flux in the Alpine Meadow Ecosystem in the Qilian Mountains, Northwest China.

Alpine meadows are vital ecosystems on the Qinghai-Tibet Plateau, significantly contributing to water conservation and climate regulation. This study examines the energy flux patterns and their driving factors in the alpine meadows of the Qilian Mountains, focusing on how the meteorological variables of net radiation (), air temperature, vapor pressure deficit (), wind speed (), and soil water content () influence sensible heat flux () and latent heat flux (). Using the Bowen ratio energy balance method, we monitored energy changes during the growing and non-growing seasons from 2022 to 2023.

Transposable elements shape the landscape of heterozygous structural variation in a bird genome.

Avian genomes exhibit compact organization and remarkable chromosomal stability. However, the extent and mechanisms by which structural variation in avian genomes differ from those in other vertebrate lineages are poorly explored. This study generated a diploid genome assembly for the golden pheasant ( ), a species distinguished by the vibrant plumage of males.

Effects of feeding of vitamin C on embryonic development, hatching process, and chick rectal temperature of broiler embryos.

Maternal nutritional status plays a crucial role in embryonic development and has persistent effects on postnatal chicks. Vitamin C (VC) plays an important role in embryonic and postnatal development involved in nutri-epigenetics. The present study was conducted to investigate the effects of feeding (IOF) of VC on embryonic development, egg hatching time, and chick rectal temperature.

Prevalence of Site-Specific Infection and Macrolide and Fluoroquinolone-Associated Mutations in Men Who Have Sex with Men in Shenzhen, China.

Background: (MG) poses a growing public health concern due to the escalating antimicrobial resistance. We aimed to assess site-specific MG infection and its correlates and macrolide and fluoroquinolones mutations among men who have sex with men (MSM) in Shenzhen, China.

Methods: Samples were obtained from different anatomic sites of MSM based on their sexual behavior.

Genome-wide association study identifies candidate genes affecting body conformation traits of Zhongwei goat.

Background: Identifying markers or genes crucial for growth traits in Zhongwei goats is pivotal for breeding. Pinpointing genetic factors linked to body size gain enhances breeding efficiency and economic value. In this study, we used the MGISEQ-T7 platform to re-sequence 240 Zhongwei goats (133 male; 107 female) belonging to 5 metrics of growth traits at different growth stages (40 days and 6 months, here in after referred to as 40d and 6 m), namely, Body Weight (BW), Body Height (BH), Body Length (BL), Chest Circumference (CC), Tube Circumference (TC) were examined.

Exploring the influence of age on the causes of death in advanced nasopharyngeal carcinoma patients undergoing chemoradiotherapy using machine learning methods.

The present study analyzed the impact of age on the causes of death (CODs) in patients with nasopharyngeal carcinoma (NPC) undergoing chemoradiotherapy (CRT) using machine learning approaches. A total of 2841 patients (1037 classified as older, ≥ 60 years and 1804 as younger, < 60 years) were enrolled. Variations in the CODs between the two age groups were analyzed before and after applying inverse probability of treatment weighting (IPTW).

Atomically Dispersed Metal-Nitrogen-Carbon Catalysts for Acidic Oxygen Reduction Reaction.

Designing efficient and cost-effective electrocatalysts toward oxygen reduction reaction (ORR) under demanding acidic environments plays a critical role in advancing proton exchange membrane fuel cells (PEMFCs). Metal-nitrogen-carbon (M-N-C) catalysts with atomically dispersed metals have gained attention for their affordability, excellent catalytic performance, and distinctive features including consistent active sites and high atomic utilization. Over the past decade, significant achievements have been made in this field.

Cation-Modulated Ni/NiN Compound Heterojunctions as Highly Efficient Bifunctional Electrocatalysts for Water Splitting.

The exploration and rational design of high-performance, durable, and non-precious-metal bifunctional oxygen electrocatalysts are highly desired for the large-scale application of overall water splitting. Herein, an effective and straightforward coupling approach was developed to fabricate high-performance bifunctional OER/HER electrocatalysts based on core-shell nanostructure comprising a Ni/NiN core and a NiFe(OH) shell. The as-prepared Ni/NiN@NiFe(OH)-4 catalyst exhibited low overpotentials of 57 and 243 mV at 10 mA cm for the HER and OER in 1.

Rare variant association studies: Significance, methods, and applications in chronic pain studies.

Rare genetic variants, characterized by their low frequency in a population, have emerged as essential components in the study of complex disease genetics. The biology of rare variants underscores their significance, as they can exert profound effects on phenotypic variation and disease susceptibility. Recent advancements in sequencing technologies have yielded the availability of large-scale sequencing data such as the UK Biobank whole-exome sequencing (WES) cohort empowered researchers to conduct rare variant association studies (RVASs).

Decoding the prognostic landscape of LUAD: the interplay between N-methyladenosine modification and immune microenvironment.

Background: To determine the role of N-methyladenosine (mA) modification in the tumor immune microenvironment (TIME), as well as their association with lung adenocarcinoma (LUAD).

Methods: Consensus clustering was performed to identify the subgroups with distinct immune or mA modification patterns using profiles from TCGA. A risk score model was constructed using least absolute shrinkage and selection operator regression and validated in two independent cohorts and LUAD tissue microarrays.

m6A methyltransferase METTL3 promotes non-small-cell lung carcinoma progression by inhibiting the RIG-I-MAVS innate immune pathway.

Our experimental study showed that METTL3 was highly expressed in NSCLC cells and promoted the growth of tumor cells. METTL3 takes N6-methyladenosine (m6A) as the main means of mRNA modification to control the expression and function of RIG-I-MAVS signalling pathway. RIG-I-MAVS constitute the first line frontier in the innate immune defense of human cells.

Exploring the impact of physical exercise on mental health among female college students: the chain mediating role of coping styles and psychological resilience.

Background: Female college students are a high-risk group for psychological conflicts, and they are more likely to adopt negative coping styles under stress, which can lead to anxiety, depression, and other psychological problems, as well as pose hidden threats to the healthy development of school education and social work. Although physical exercise is an important means of effectively alleviating the psychological health of female college students, and there may be a close relationship between coping styles and psychological resilience with physical exercise and psychological health, specific ways to promote the psychological health of female college students by influencing their coping styles and enhancing their psychological resilience have yet to be explored.

Methods: The present study employed a cross-sectional design to investigate a sample of Chinese undergraduate female college students.

Mast cell activation by NGF drives the formation of trauma-induced heterotopic ossification.

Soft tissue trauma can cause immune system disturbance and neuropathological invasion, resulting in heterotopic ossification (HO) due to aberrant chondrogenic differentiation of mesenchymal stem cells (MSCs). However, the molecular mechanisms behind the interaction between the immune and nervous systems in promoting HO pathogenesis are unclear. In this study, we found that mast cell-specific deletion attenuated localized tissue inflammation, with marked inhibition of HO endochondral osteogenesis.

High-precision DSM-based laser ranging method integrated with free space optical communication.

Free space optical communication (FSOC) technology has been developed rapidly and practically applied in many scenarios such as satellite-related ones, in unmanned aerial vehicles, for underwater use, etc. In certain applications, it is very important to obtain the high-precision position and distance information. The laser ranging technology is one of the main ways to realize it.

Root morphology, nitrogen metabolism and amino acid metabolism in soybean under low phosphorus stress.

Phosphorus deficiency is a major influence on growth and development of soybean. Therefore, improving phosphorus utilization efficiency in soybean is a research priority for the soybean community. In this experiment, Liaodou 13 (high phosphorus utilization: HPE) and Tiefeng 3 (low phosphorus utilization: LPE) were used as test varieties.

C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade.

Core1 β1,3-galactosyltransferase (C1GALT1) is an essential glycotransferase controlling the elongation of GalNAc-type O-glycosylation and its altered expression contributes tumor progression in various cancers. However, the mechanism how C1GALT1 influences gliomas remains unclear. Here，our results from The Cancer Genome Atlas (TCGA) database, The Chinese Glioma Genome Atlas (CGGA) database and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) database showed that the expression of C1GALT1 was increased in higher grade gliomas namely glioblastoma compared with low grade gliomas or non-tumor tissues and significantly associated with poor survival.

mA-modified circCacna1c regulates necroptosis and ischemic myocardial injury by inhibiting Hnrnpf entry into the nucleus.

Background: Circular RNAs (circRNAs) are differentially expressed in various cardiovascular diseases, including myocardial infarction (MI) injury. However, their functional role in necroptosis-induced loss of cardiomyocytes remains unclear. We identified a cardiac necroptosis-associated circRNA transcribed from the Cacna1c gene (circCacna1c) to investigate the involvement of circRNAs in cardiomyocyte necroptosis.

A novel cold-adapted pyrethroid-degrading esterase from Bacillus subtilis J6 and its application for pyrethroid-residual alleviation in food matrix.

Prolonged and widespread use of pyrethroid pesticides a significant concern for human health. The initial step in pyrethroid bioremediation involves the hydrolysis of ester-bond. In the present study, the esterase genes est10 and est13, derived from Bacillus subtilis, were successfully cloned and expressed in Escherichia coli.

Dealing with job search reactions: How strength of music preference predicts job seekers' stress and knowledge-skill development.

This research investigates the relationship between music preference strength and job search reactions, specifically stress and knowledge-skill development, with career adaptability as a mediating factor. Results obtained using a two-wave data collection procedure (wave one: N = 337; wave two: N = 188; the final sample size after matching: N = 182) reveal that music preference strength is positively correlated with career adaptability, which significantly mediates the relationship between music preference strength and both lower job search stress and greater knowledge-skill development. These findings suggest that fostering strong music preferences is associated with enhanced career adaptability, which predicts reduced stress and improved skill development during job searches.

Biological characterization and fungicide screening of a new causal agent of walnut leaf spot in Guizhou Province, China.

Walnut ( L.) is a widely grown nut plant worldwide, including in Guizhou Province, located in southwest China. The high quality and special taste make Guizhou walnuts, particularly those produced in Hezhang County, a "Chinese National Geographical Indication Product" that substantially contributes to the local economy and grower's income.

Algorithm Analysis and Optimization of a Digital Image Correlation Method Using a Non-Probability Interval Multidimensional Parallelepiped Model.

Digital image correlation (DIC), a widely used non-contact measurement technique, often requires empirical tuning of several algorithmic parameters to strike a balance between computational accuracy and efficiency. This paper introduces a novel uncertainty analysis approach aimed at optimizing the parameter intervals of a DIC algorithm. Specifically, the method leverages the inverse compositional Gauss-Newton algorithm combined with a prediction-correction scheme (IC-GN-PC), considering three critical parameters as interval variables.