Engineering the metabolism and morphology of the filamentous fungus Trichoderma reesei for efficient L-malic acid production.

L-malic acid (MA) is a vital platform chemical with huge market demand because of its broad industrial applications. A cell factory for MA production was engineered by strengthening the intrinsic pathway without inserting foreign genes into Trichoderma reesei. The native MA transporter gene in the T.

Metabolic Engineering of for l-Malic Acid Production.

l-Malic acid has various applications in the chemical and food industries. The filamentous fungus is known to be an efficient enzyme producer. Here, through metabolic engineering, was constructed for the first time as an excellent cell factory for l-malic acid production.