[Healthy person's cerebral reactions to the rhythmic transcranial magnetic stimulation of different intensity].

At 8 healthy examinees-volunteers of 22-25 years the functional effects of super-threshold (above 1.2 T) and subthreshold (70-80% of a motor threshold) rTMS of premotor cortexes medial departments were compared. Functional brain activity changes were estimated (before and 1 hour after stimulation) by comparing data including neuropsychological testing, visual and spectral-coherent EEG-analysis, and also haemodynamic parameters.

[Cerebral circulatory autoregulation as a guide for controlling the parameters of assisted ventilation in acute severe brain injury].

The paper presents the results of cerebral circulation (CC) in 17 ventilated patients with severe brain injury in its acute phase. All the patients developed traumatic subarachnoidal hemorrhage, which was accompanied with angiospasm in the majority of cases. Doppler transcranial study (DTCS) was performed, by using the carotid compression test; the findings correlated with paCO2 and CV parameters.

[The orthostatic resistance of the cerebral and peripheral circulations in patients with contusive brain lesions].

Orthostatic tests with printing recording of EEG, REG, RVG were used to examine the functional status of the truncal level of circulatory regulation in patients with brain confusions. Within the first 24 hours after brain injury there was a significant reduction in the pulse blood filling of cerebral vessels in the vascularization areas of carotid and vertebral arteries along with higher vascular tone; pulse blood filling of peripheral vessels in the lower extremities remained normal with a marked decrease in their vascular tone. Orthostatic tests showed the asymmetric enhancement of a dilating arterial response in the virtual absence of a constrictive response of lower extremity vessels.

[The use of sodium nitroprusside in the anesthesiological support of cerebral angiography].

Complex study of the effect of sodium nitroprusside intra-arterial and intravenous infusion under local and general anesthesia on the cerebral, peripheral, and general hemodynamics during cerebral angiography was carried out in 43 patients with neurosurgical pathology (17 females and 26 males from 17 to 58 years of age). The authors proved the efficacy of intraarterial and, to a lesser measure, of intravenous sodium nitroprusside infusion in relieving spasm of the cerebral arteries developing during cerebral angiography.

[Regulation of cerebral circulation in an upright posture of the human trunk].

The functional mechanisms responsible for orthostatic tolerance of cerebral circulation in the normal man and in ambulatory and bedridden neurosurgical patients were investigated, using the following methods: cerebral blood flow by means of xenon-133 clearance, measurement of brain perfusion pressure, ventricular pressure, acid-base equilibrium in the blood flowing in and out of the brain, determination of cardiac output and stroke volume, electroencephalography, and rheography of cerebral and peripheral vessels. In the normal men and patients with compensated neurosurgical pathologies, the transfer into the head-up position induced small changes in the systemic and cerebral regional circulation. This was associated with complex reactions of the vascular system triggered by the receptors of the sinocarotid area.

[Complex experimental and clinical study of the effect of nitroglycerin on the cerebral, peripheral and systemic circulations].

Experiments on anesthetized and unanesthetized cats and examination of 42 neurosurgical patients have shown that nitroglycerin considerably increases cerebral and peripheral circulation, raises the pressure in the internal jugular vein and brain ventricles, increases the lumen of cerebral vessels of predominantly minor caliber, speeds up the linear and volumetric rate of the cerebral blood flow. Nitroglycerin induces a decrease in the systemic arterial and perfusion pressure. No species differences in the manifestations of the nitroglycerin pharmacological effect confirmed in the principle the common organization of the adrenergic mechanisms that control the cardiovascular system.

[Complex study of the hemodynamics, impedance, and bioelectrical activity of the brain of patients with parasagittal meningiomas].

Combined use of radioisotope and impedance methods in the examination of cerebral and peripheral circulation and EEG recording in 40 patients with parasagittal meningiomas revealed a correlation between the rheographic characteristics of the tonus and blood filling of the cerebral vessels and the quantitative values of cerebral hemodynamics. Specific features of cerebral circulatory disorders characteristic of parasagittal tumors were revealed before operation and in the postoperative period. The prognostic significance of examination of the cerebral blood flow and impedance in the early postoperative period is demonstrated.

[Clinico-physiologic analysis of the effect of decompressing the cerebrospinal fluid system in children with hydrocephalus].

Changes in vascular tonicity and blood filling in the brain were studied in 26 children with occlusive hydrocephalus during ventricular punctures and following surgical elimination of the occlusion. The nature of the reactive changes in the tonicity and blood filling of the cerebral and peripheral vessels was found to be different in response to the draining of the CSF system depending on the level of thebrain lesion. Following ventricular punctures with CSF draining the majority of the examined demonstrated a normalization of their elevated tonicity of the cerebral vessels and a disappearance of hampered venous drainage.

[Correlation between the circulation of the hemispheres and brain stem regions, the peripheral circulation and bioelectrical activity of the brain in the dynamics of the acute period of cranio-cerebral injury].

Polygraphic recording of rheoencephalography, rheovasography and EEG was used for a dynamic examination of 45 patients with severe (28 cases) and moderate (17 cases) craniocerebral injuries. In 13 patients, of the former group intracranial haematomas were noted, in 15--contusion foci. A method of rheoencephalography recording from the brain stem with the aid of a basal electrode was developed, and it permitted to obtain valuable information on the degree of the haemodynamic shifts in the brain stem.

[The adequacy of the rheoencephalographic method in clinical practice and research].

For purposes of defining the adequacy of using REG registrations in clinical practice, the authors conducted 4 series of studies on normals (16 cases), in patients of a neurosurgical ward (39 cases) and in experimental animals (12 dogs). The experimental and clinical studies displayed that the mechanical pulse fluctuation of the skin was not the determining factor in the genesis of a REG. The authors have come to the conclusion that the time of distribution of the pulse wave by itself can not serve as an indicator of an extra-or intracranial origination of REG waves inasmuch as it is different in different brain areas and depending upon its remoteness from the heart and the state of the vascular tone.