J Labelled Comp Radiopharm
September 2019
This study aims at analyzing complexation properties of two new short somatostatin analogues, their synthesis, radiolabeling with Sc, Bi, and Eu and stability in vitro. Short tetrapeptide Phe-d-Trp-Lys-Thr and pentapeptide Thz-Phe-d-Trp-Lys-Thr were first conjugated with the DOTA macrocyclic chelator. These conjugates were radiolabeled with Sc, Bi, and Eu and characterized by thin-layer chromatography (TLC) and HPLC.
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