In vitro study examining the effectiveness of antiseptic prophylaxis for antibiotic-resistant bacterial endophthalmitis.

Purpose: To assess the effectiveness of current antiseptic agents on multidrug-resistant (MDR) isolates in an in vitro setting.

Setting: Department of Microbiology, The National Maternity Hospital, Dublin, Ireland.

Design: Organisms were selected based on current review of endophthalmitis literature: methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), Pseudomonas aeruginosa, carbapenem-resistant and extended-spectrum β-lactamase Klebsiella pneumoniae, and vancomycin-resistant (VRE) Enterococcus faecalis.